Title |
Bone marrow derived cells in adult skeletal muscle tissue in humans
|
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Published in |
Skeletal Muscle, May 2013
|
DOI | 10.1186/2044-5040-3-12 |
Pubmed ID | |
Authors |
Anna Strömberg, Monika Jansson, Helene Fischer, Eric Rullman, Hans Hägglund, Thomas Gustafsson |
Abstract |
During the past decade, several animal studies have demonstrated that in addition to local cells, cells from the bone marrow (BM) possess the ability to contribute to regeneration of injured skeletal muscle tissue. In addition, in mice, regular physical activity has been displayed to be a sufficient stimulus for BM-derived cell contribution to the muscle, indicating that this is part of the ongoing physiological remodeling of skeletal muscle. However, whether BM-derived cells participate in human skeletal muscle remodeling is not known. To this end, we analyzed the incorporation of BM-derived cells in healthy human skeletal muscle in women transplanted with male BM. |
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