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X Demographics
Mendeley readers
Attention Score in Context
| Title |
The modulation of apoptosis by oncogenic viruses
|
|---|---|
| Published in |
Virology Journal, June 2013
|
| DOI | 10.1186/1743-422x-10-182 |
| Pubmed ID | |
| Authors |
Alma Mariana Fuentes-González, Adriana Contreras-Paredes, Joaquín Manzo-Merino, Marcela Lizano |
| Abstract |
Transforming viruses can change a normal cell into a cancer cell during their normal life cycle. Persistent infections with these viruses have been recognized to cause some types of cancer. These viruses have been implicated in the modulation of various biological processes, such as proliferation, differentiation and apoptosis. The study of infections caused by oncogenic viruses had helped in our understanding of several mechanisms that regulate cell growth, as well as the molecular alterations leading to cancer. Therefore, transforming viruses provide models of study that have enabled the advances in cancer research. Viruses with transforming abilities, include different members of the Human Papillomavirus (HPV) family, Hepatitis C virus (HCV), Human T-cell Leukemia virus (HTLV-1), Epstein Barr virus (EBV) and Kaposi's Sarcoma Herpesvirus (KSHV).Apoptosis, or programmed cell death, is a tightly regulated process that plays an important role in development and homeostasis. Additionally, it functions as an antiviral defense mechanism. The deregulation of apoptosis has been implicated in the etiology of diverse diseases, including cancer. Oncogenic viruses employ different mechanisms to inhibit the apoptotic process, allowing the propagation of infected and damaged cells. During this process, some viral proteins are able to evade the immune system, while others can directly interact with the caspases involved in apoptotic signaling. In some instances, viral proteins can also promote apoptosis, which may be necessary for an accurate regulation of the initial stages of infection. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | 50% |
| United States | 1 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 113 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Mexico | 1 | <1% |
| Portugal | 1 | <1% |
| Denmark | 1 | <1% |
| Brazil | 1 | <1% |
| Unknown | 109 | 96% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 25 | 22% |
| Student > Bachelor | 19 | 17% |
| Student > Master | 18 | 16% |
| Researcher | 12 | 11% |
| Student > Doctoral Student | 9 | 8% |
| Other | 17 | 15% |
| Unknown | 13 | 12% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 36 | 32% |
| Medicine and Dentistry | 25 | 22% |
| Biochemistry, Genetics and Molecular Biology | 16 | 14% |
| Immunology and Microbiology | 9 | 8% |
| Neuroscience | 2 | 2% |
| Other | 8 | 7% |
| Unknown | 17 | 15% |
Attention Score in Context
This research output has an Altmetric Attention Score of 14. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 02 February 2022.
All research outputs
#2,296,371
of 23,041,514 outputs
Outputs from Virology Journal
#193
of 3,063 outputs
Outputs of similar age
#20,618
of 198,489 outputs
Outputs of similar age from Virology Journal
#7
of 105 outputs
Altmetric has tracked 23,041,514 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 90th percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 3,063 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 25.7. This one has done particularly well, scoring higher than 93% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 198,489 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 89% of its contemporaries.
We're also able to compare this research output to 105 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 93% of its contemporaries.