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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Exosomes secreted by human cells transport largely mRNA fragments that are enriched in the 3′-untranslated regions
|
|---|---|
| Published in |
Biology Direct, June 2013
|
| DOI | 10.1186/1745-6150-8-12 |
| Pubmed ID | |
| Authors |
Arsen O Batagov, Igor V Kurochkin |
| Abstract |
Small secreted membrane vesicles called exosomes have recently attracted a great interest after the discovery that they transfer mRNA that can be translated into protein in recipient cells. Surprisingly, we found that for the majority of exosomal mRNAs only a fraction of their corresponding probes is detectable on the expression microarrays. Exosomal mRNA fragmentation is characterized with a specific structural pattern. The closer to the 3'-end of the transcript the fragments are localized, the larger fraction among the secreted RNAs they constitute. Since the 3'-ends of transcripts contain elements conferring subcellular localization of mRNA and are rich in miRNA-binding sites, exosomal RNA may act as competing RNA to regulate stability, localization and translation activity of mRNAs in recipient cells. |
X Demographics
The data shown below were collected from the profiles of 17 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 5 | 29% |
| United States | 3 | 18% |
| Brazil | 1 | 6% |
| Unknown | 8 | 47% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 15 | 88% |
| Science communicators (journalists, bloggers, editors) | 1 | 6% |
| Scientists | 1 | 6% |
Mendeley readers
The data shown below were compiled from readership statistics for 296 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 5 | 2% |
| Germany | 2 | <1% |
| Sweden | 1 | <1% |
| France | 1 | <1% |
| Canada | 1 | <1% |
| Czechia | 1 | <1% |
| Unknown | 285 | 96% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 73 | 25% |
| Researcher | 48 | 16% |
| Student > Master | 33 | 11% |
| Student > Bachelor | 26 | 9% |
| Student > Doctoral Student | 22 | 7% |
| Other | 33 | 11% |
| Unknown | 61 | 21% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 83 | 28% |
| Biochemistry, Genetics and Molecular Biology | 65 | 22% |
| Medicine and Dentistry | 32 | 11% |
| Engineering | 9 | 3% |
| Immunology and Microbiology | 8 | 3% |
| Other | 22 | 7% |
| Unknown | 77 | 26% |
Attention Score in Context
This research output has an Altmetric Attention Score of 20. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 24 December 2021.
All research outputs
#1,888,716
of 25,836,587 outputs
Outputs from Biology Direct
#58
of 540 outputs
Outputs of similar age
#15,521
of 210,892 outputs
Outputs of similar age from Biology Direct
#2
of 5 outputs
Altmetric has tracked 25,836,587 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 92nd percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 540 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 10.5. This one has done well, scoring higher than 89% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 210,892 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 92% of its contemporaries.
We're also able to compare this research output to 5 others from the same source and published within six weeks on either side of this one. This one has scored higher than 3 of them.