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Challenges in orphan drug development and regulatory policy in China

Overview of attention for article published in Orphanet Journal of Rare Diseases, January 2017
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  • Above-average Attention Score compared to outputs of the same age and source (52nd percentile)

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Citations

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Title
Challenges in orphan drug development and regulatory policy in China
Published in
Orphanet Journal of Rare Diseases, January 2017
DOI 10.1186/s13023-017-0568-6
Pubmed ID
Authors

Alice Cheng, Zhi Xie

Abstract

While regulatory policy is well defined for orphan drug development in the United States and Europe, rare disease policy in China is still evolving. Many Chinese patients currently pay out of pocket for international treatments that are not yet approved in China. The lack of a clear definition and therefore regulatory approval process for rare diseases has, until now, de-incentivized pharmaceutical companies to pursue rare disease drug development in China. In turn, many grassroots movements have begun to support rare disease patients and facilitate drug discovery through research. Recently, the Chinese FDA set new regulatory guidelines for drugs being developed in China, including an expedited review process for life-saving treatments. In this review, we discuss the effects of these new policy changes on and suggest potential solutions to innovate orphan drug development in China.

X Demographics

X Demographics

The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 47 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 47 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 7 15%
Student > Master 6 13%
Other 5 11%
Student > Bachelor 4 9%
Researcher 3 6%
Other 4 9%
Unknown 18 38%
Readers by discipline Count As %
Pharmacology, Toxicology and Pharmaceutical Science 9 19%
Nursing and Health Professions 6 13%
Medicine and Dentistry 4 9%
Business, Management and Accounting 2 4%
Biochemistry, Genetics and Molecular Biology 2 4%
Other 6 13%
Unknown 18 38%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 02 March 2017.
All research outputs
#13,292,187
of 22,940,083 outputs
Outputs from Orphanet Journal of Rare Diseases
#1,360
of 2,635 outputs
Outputs of similar age
#205,386
of 418,282 outputs
Outputs of similar age from Orphanet Journal of Rare Diseases
#23
of 48 outputs
Altmetric has tracked 22,940,083 research outputs across all sources so far. This one is in the 41st percentile – i.e., 41% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,635 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 7.6. This one is in the 46th percentile – i.e., 46% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 418,282 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 50% of its contemporaries.
We're also able to compare this research output to 48 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 52% of its contemporaries.