Title |
History of sentinel node and validation of the technique
|
---|---|
Published in |
Breast Cancer Research, April 2001
|
DOI | 10.1186/bcr281 |
Pubmed ID | |
Authors |
Pieter J Tanis, Omgo E Nieweg, Renato A Valdés Olmos, Emiel J Th Rutgers, Bin BR Kroon |
Abstract |
Sentinel node biopsy is a minimally invasive technique to select patients with occult lymph node metastases who may benefit from further regional or systemic therapy. The sentinel node is the first lymph node reached by metastasising cells from a primary tumour. Attempts to remove this node with a procedure based on standard anatomical patterns did not become popular. The development of the dynamic technique of intraoperative lymphatic mapping in the 1990s resulted in general acceptance of the sentinel node concept. This hypothesis of sequential tumour dissemination seems to be valid according to numerous studies of sentinel node biopsy with confirmatory regional lymph node dissection. This report describes the history and the validation of the technique, with particular reference to breast cancer. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 1 | <1% |
Denmark | 1 | <1% |
Slovakia | 1 | <1% |
Unknown | 137 | 98% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Doctoral Student | 23 | 16% |
Student > Ph. D. Student | 17 | 12% |
Student > Bachelor | 17 | 12% |
Student > Master | 14 | 10% |
Researcher | 13 | 9% |
Other | 33 | 24% |
Unknown | 23 | 16% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 79 | 56% |
Biochemistry, Genetics and Molecular Biology | 7 | 5% |
Agricultural and Biological Sciences | 5 | 4% |
Nursing and Health Professions | 3 | 2% |
Engineering | 3 | 2% |
Other | 10 | 7% |
Unknown | 33 | 24% |