As @AMeynert et al showed on what was presumably a now fairly obsolete pipe, sensitivity for homozygous and homozygous SNVs is >80% with just 2 reads, and >95% with 3. Specificity reaches its asymptote at 5 or 6. https://t.co/7S7EEENdly 7/n
592 followers
122 followers
Quantifying single nucleotide variant detection sensitivity in #exome sequencing http://t.co/Emh6EQUO4c #bmcbioinformatics
188 followers
"...SeqCap EZ solution-based kit also generates more uniform coverage than Agilent kits" Read the pub now: http://t.co/OCQFhMF71V
93 followers
Dont use average coverage! Quantifying SNV detection sensitivity in #exome #sequencing http://t.co/LYUCIk57Jf #bioinformatics #genomics #NGS