Title |
Short-course radiotherapy followed by neo-adjuvant chemotherapy in locally advanced rectal cancer – the RAPIDO trial
|
---|---|
Published in |
BMC Cancer, June 2013
|
DOI | 10.1186/1471-2407-13-279 |
Pubmed ID | |
Authors |
Per J Nilsson, Boudewijn van Etten, Geke AP Hospers, Lars Påhlman, Cornelis JH van de Velde, Regina GH Beets-Tan, Lennart Blomqvist, Jannet C Beukema, Ellen Kapiteijn, Corrie AM Marijnen, Iris D Nagtegaal, Theo Wiggers, Bengt Glimelius |
Abstract |
Current standard for most of the locally advanced rectal cancers is preoperative chemoradiotherapy, and, variably per institution, postoperative adjuvant chemotherapy. Short-course preoperative radiation with delayed surgery has been shown to induce tumour down-staging in both randomized and observational studies. The concept of neo-adjuvant chemotherapy has been proven successful in gastric cancer, hepatic metastases from colorectal cancer and is currently tested in primary colon cancer. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 5 | 28% |
Spain | 2 | 11% |
United Kingdom | 2 | 11% |
Australia | 2 | 11% |
Singapore | 1 | 6% |
India | 1 | 6% |
Unknown | 5 | 28% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 9 | 50% |
Practitioners (doctors, other healthcare professionals) | 5 | 28% |
Scientists | 3 | 17% |
Science communicators (journalists, bloggers, editors) | 1 | 6% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 2 | <1% |
Slovakia | 1 | <1% |
Germany | 1 | <1% |
Japan | 1 | <1% |
Belgium | 1 | <1% |
Unknown | 240 | 98% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 42 | 17% |
Other | 29 | 12% |
Student > Postgraduate | 25 | 10% |
Student > Doctoral Student | 25 | 10% |
Student > Ph. D. Student | 21 | 9% |
Other | 51 | 21% |
Unknown | 53 | 22% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 141 | 57% |
Nursing and Health Professions | 5 | 2% |
Agricultural and Biological Sciences | 4 | 2% |
Immunology and Microbiology | 4 | 2% |
Engineering | 4 | 2% |
Other | 21 | 9% |
Unknown | 67 | 27% |