Title |
Predicting complex traits using a diffusion kernel on genetic markers with an application to dairy cattle and wheat data
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Published in |
Genetics Selection Evolution, June 2013
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DOI | 10.1186/1297-9686-45-17 |
Pubmed ID | |
Authors |
Gota Morota, Masanori Koyama, Guilherme J M Rosa, Kent A Weigel, Daniel Gianola |
Abstract |
Arguably, genotypes and phenotypes may be linked in functional forms that are not well addressed by the linear additive models that are standard in quantitative genetics. Therefore, developing statistical learning models for predicting phenotypic values from all available molecular information that are capable of capturing complex genetic network architectures is of great importance. Bayesian kernel ridge regression is a non-parametric prediction model proposed for this purpose. Its essence is to create a spatial distance-based relationship matrix called a kernel. Although the set of all single nucleotide polymorphism genotype configurations on which a model is built is finite, past research has mainly used a Gaussian kernel. |
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Researcher | 7 | 15% |
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Other | 2 | 4% |
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