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Cubilin expression is monoallelic and epigenetically augmented via PPARs

Overview of attention for article published in BMC Genomics, June 2013
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Title
Cubilin expression is monoallelic and epigenetically augmented via PPARs
Published in
BMC Genomics, June 2013
DOI 10.1186/1471-2164-14-405
Pubmed ID
Authors

Obaidullah Aseem, Jeremy L Barth, Sandra C Klatt, Brian T Smith, W Scott Argraves

Abstract

Cubilin is an endocytic receptor that is necessary for renal and intestinal absorption of a range of ligands. Endocytosis mediated by cubilin and its co-receptor megalin is the principal mechanism for proximal tubule reabsorption of proteins from the glomerular filtrate. Cubilin is also required for intestinal endocytosis of intrinsic factor-vitamin B12 complex. Despite its importance, little is known about the regulation of cubilin expression.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 24 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 4%
Unknown 23 96%

Demographic breakdown

Readers by professional status Count As %
Researcher 5 21%
Student > Ph. D. Student 5 21%
Student > Master 3 13%
Student > Bachelor 2 8%
Lecturer > Senior Lecturer 1 4%
Other 2 8%
Unknown 6 25%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 7 29%
Agricultural and Biological Sciences 5 21%
Medicine and Dentistry 3 13%
Pharmacology, Toxicology and Pharmaceutical Science 2 8%
Immunology and Microbiology 1 4%
Other 1 4%
Unknown 5 21%