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Contribution of different classes of glutamate receptors in the corticostriatal polysynaptic responses from striatal direct and indirect projection neurons

Overview of attention for article published in BMC Neuroscience, June 2013
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  • Good Attention Score compared to outputs of the same age (66th percentile)
  • Good Attention Score compared to outputs of the same age and source (70th percentile)

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Title
Contribution of different classes of glutamate receptors in the corticostriatal polysynaptic responses from striatal direct and indirect projection neurons
Published in
BMC Neuroscience, June 2013
DOI 10.1186/1471-2202-14-60
Pubmed ID
Authors

Bianca J Vizcarra-Chacón, Mario A Arias-García, Maria B Pérez-Ramírez, Edén Flores-Barrera, Dagoberto Tapia, Rene Drucker-Colin, José Bargas, Elvira Galarraga

Abstract

Previous work showed differences in the polysynaptic activation of GABAergic synapses during corticostriatal suprathreshold responses in direct and indirect striatal projection neurons (dSPNs and iSPNs). Here, we now show differences and similarities in the polysynaptic activation of cortical glutamatergic synapses on the same responses. Corticostriatal contacts have been extensively studied. However, several questions remain unanswered, e.g.: what are the differences and similarities in the responses to glutamate in dSPNs and iSPNs? Does glutamatergic synaptic activation exhibits a distribution of latencies over time in vitro? That would be a strong suggestion of polysynaptic cortical convergence. What is the role of kainate receptors in corticostriatal transmission? Current-clamp recordings were used to answer these questions. One hypothesis was: if prolonged synaptic activation distributed along time was present, then it would be mainly generated from the cortex, and not from the striatum.

X Demographics

X Demographics

The data shown below were collected from the profiles of 5 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 38 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Mexico 1 3%
Unknown 37 97%

Demographic breakdown

Readers by professional status Count As %
Researcher 10 26%
Student > Ph. D. Student 9 24%
Student > Bachelor 6 16%
Professor > Associate Professor 3 8%
Student > Master 3 8%
Other 4 11%
Unknown 3 8%
Readers by discipline Count As %
Neuroscience 16 42%
Agricultural and Biological Sciences 12 32%
Medicine and Dentistry 4 11%
Psychology 1 3%
Biochemistry, Genetics and Molecular Biology 1 3%
Other 1 3%
Unknown 3 8%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 21 June 2013.
All research outputs
#7,372,420
of 22,712,476 outputs
Outputs from BMC Neuroscience
#367
of 1,241 outputs
Outputs of similar age
#65,172
of 196,704 outputs
Outputs of similar age from BMC Neuroscience
#14
of 47 outputs
Altmetric has tracked 22,712,476 research outputs across all sources so far. This one has received more attention than most of these and is in the 67th percentile.
So far Altmetric has tracked 1,241 research outputs from this source. They receive a mean Attention Score of 4.3. This one has gotten more attention than average, scoring higher than 70% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 196,704 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 66% of its contemporaries.
We're also able to compare this research output to 47 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 70% of its contemporaries.