Title |
Association of arterial stiffness with single nucleotide polymorphism rs1333049 and metabolic risk factors
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Published in |
Cardiovascular Diabetology, June 2013
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DOI | 10.1186/1475-2840-12-93 |
Pubmed ID | |
Authors |
Suphawadee Phababpha, Upa Kukongviriyapan, Poungrat Pakdeechote, Laddawan Senggunprai, Veerapol Kukongviriyapan, Chatri Settasatian, Pyatat Tatsanavivat, Phongsak Intharaphet, Vichai Senthong, Nantarat Komanasin, Nongnuch Settasatian, Stephen E Greenwald |
Abstract |
Increased arterial stiffness is a cardiovascular outcome of metabolic syndrome (MetS). The chromosome 9p21 locus has been identified as a major locus for risk of coronary artery disease (CAD). The single nucleotide polymorphism (SNP), rs1333049 on chromosome 9p21.3 has been strongly associated with CAD and myocardial infarction. Increased arterial stiffness could be the link between the 9p21 polymorphism and increased cardiovascular risk. Since the impact of a genetic polymorphism on arterial stiffness especially in Asian populations has not been well defined, we aimed to investigate the association of arterial stiffness with rs 1333049 variant on chromosome 9p21.3 in Thai subjects with and without MetS risk factors. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 1 | 20% |
India | 1 | 20% |
United States | 1 | 20% |
Thailand | 1 | 20% |
Unknown | 1 | 20% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 5 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Sri Lanka | 1 | 3% |
Unknown | 36 | 97% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 8 | 22% |
Student > Ph. D. Student | 5 | 14% |
Lecturer | 2 | 5% |
Researcher | 2 | 5% |
Student > Bachelor | 2 | 5% |
Other | 4 | 11% |
Unknown | 14 | 38% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 7 | 19% |
Nursing and Health Professions | 6 | 16% |
Agricultural and Biological Sciences | 4 | 11% |
Social Sciences | 1 | 3% |
Materials Science | 1 | 3% |
Other | 1 | 3% |
Unknown | 17 | 46% |