Title |
Incidence of bone metastases and skeletal-related events in breast cancer patients: A population-based cohort study in Denmark
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Published in |
BMC Cancer, January 2011
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DOI | 10.1186/1471-2407-11-29 |
Pubmed ID | |
Authors |
Annette Ø Jensen, Jacob B Jacobsen, Mette Nørgaard, Mellissa Yong, Jon P Fryzek, Henrik T Sørensen |
Abstract |
Breast cancer (BrCa) is the most commonly diagnosed cancer among women in the industrialized world. More than half of women presenting with metastatic BrCa develop bone metastases. Bone metastases increase the risk of skeletal-related events (SREs), defined as pathological fractures, spinal cord compression, bone pain requiring palliative radiotherapy, and orthopaedic surgery. Both bone metastases and SREs are associated with unfavorable prognosis and greatly affect quality of life. Few epidemiological data exist on SREs after primary diagnosis of BrCa and subsequent bone metastasis. We therefore estimated the incidence of bone metastases and SREs in newly-diagnosed BrCa patients in Denmark from 1999 through 2007. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Netherlands | 1 | <1% |
Unknown | 125 | 99% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 20 | 16% |
Researcher | 18 | 14% |
Student > Master | 13 | 10% |
Student > Bachelor | 9 | 7% |
Other | 9 | 7% |
Other | 21 | 17% |
Unknown | 36 | 29% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 51 | 40% |
Agricultural and Biological Sciences | 11 | 9% |
Engineering | 4 | 3% |
Nursing and Health Professions | 3 | 2% |
Sports and Recreations | 3 | 2% |
Other | 15 | 12% |
Unknown | 39 | 31% |