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Using ancestral information to detect and localize quantitative trait loci in genome-wide association studies

Overview of attention for article published in BMC Bioinformatics, June 2013
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Title
Using ancestral information to detect and localize quantitative trait loci in genome-wide association studies
Published in
BMC Bioinformatics, June 2013
DOI 10.1186/1471-2105-14-200
Pubmed ID
Authors

Katherine L Thompson, Laura S Kubatko

Abstract

In mammalian genetics, many quantitative traits, such as blood pressure, are thought to be influenced by specific genes, but are also affected by environmental factors, making the associated genes difficult to identify and locate from genetic data alone. In particular, the application of classical statistical methods to single nucleotide polymorphism (SNP) data collected in genome-wide association studies has been especially challenging. We propose a coalescent approach to search for SNPs associated with quantitative traits in genome-wide association study (GWAS) data by taking into account the evolutionary history among SNPs.

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X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 27 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Germany 1 4%
Unknown 26 96%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 8 30%
Researcher 5 19%
Professor 3 11%
Student > Master 3 11%
Professor > Associate Professor 3 11%
Other 2 7%
Unknown 3 11%
Readers by discipline Count As %
Agricultural and Biological Sciences 13 48%
Computer Science 4 15%
Biochemistry, Genetics and Molecular Biology 3 11%
Engineering 2 7%
Nursing and Health Professions 1 4%
Other 0 0%
Unknown 4 15%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 21 June 2013.
All research outputs
#17,690,153
of 22,712,476 outputs
Outputs from BMC Bioinformatics
#5,919
of 7,259 outputs
Outputs of similar age
#141,309
of 196,704 outputs
Outputs of similar age from BMC Bioinformatics
#76
of 89 outputs
Altmetric has tracked 22,712,476 research outputs across all sources so far. This one is in the 19th percentile – i.e., 19% of other outputs scored the same or lower than it.
So far Altmetric has tracked 7,259 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.4. This one is in the 13th percentile – i.e., 13% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 196,704 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 24th percentile – i.e., 24% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 89 others from the same source and published within six weeks on either side of this one. This one is in the 4th percentile – i.e., 4% of its contemporaries scored the same or lower than it.