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Mendeley readers
| Title |
Cyclin D1 cooperates with p21 to regulate TGFβ-mediated breast cancer cell migration and tumor local invasion
|
|---|---|
| Published in |
Breast Cancer Research, June 2013
|
| DOI | 10.1186/bcr3441 |
| Pubmed ID | |
| Authors |
Meiou Dai, Amal A Al-Odaini, Nadège Fils-Aimé, Manuel A Villatoro, Jimin Guo, Ani Arakelian, Shafaat A Rabbani, Suhad Ali, Jean Jacques Lebrun |
| Abstract |
Deregulation of the cell cycle machinery is often found in human cancers. Modulations in the cell cycle regulator function and expression result not only in proliferative advantages, but also lead to tumor progression and invasiveness of the cancer. In particular, cyclin D1 and p21 are often over-expressed in human cancers, correlating with high tumor grade, poor prognosis and increased metastasis. This prompted us to investigate the role of the cyclin D1/p21 signaling axis downstream of transforming growth factor beta (TGFβ) in breast cancer progression. |
Mendeley readers
The data shown below were compiled from readership statistics for 135 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Mexico | 1 | <1% |
| United States | 1 | <1% |
| Sweden | 1 | <1% |
| Denmark | 1 | <1% |
| Unknown | 131 | 97% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 42 | 31% |
| Other | 25 | 19% |
| Student > Ph. D. Student | 16 | 12% |
| Student > Bachelor | 13 | 10% |
| Student > Master | 9 | 7% |
| Other | 8 | 6% |
| Unknown | 22 | 16% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 65 | 48% |
| Biochemistry, Genetics and Molecular Biology | 21 | 16% |
| Medicine and Dentistry | 10 | 7% |
| Immunology and Microbiology | 4 | 3% |
| Neuroscience | 3 | 2% |
| Other | 7 | 5% |
| Unknown | 25 | 19% |