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X Demographics
Mendeley readers
| Title |
Macromolecular juggling by ubiquitylation enzymes
|
|---|---|
| Published in |
BMC Biology, June 2013
|
| DOI | 10.1186/1741-7007-11-65 |
| Pubmed ID | |
| Authors |
Sonja Lorenz, Aaron J Cantor, Michael Rape, John Kuriyan |
| Abstract |
The posttranslational modification of target proteins with ubiquitin and ubiquitin-like proteins is accomplished by the sequential action of E1, E2, and E3 enzymes. Members of the E1 and E3 enzyme families can undergo particularly large conformational changes during their catalytic cycles, involving the remodeling of domain interfaces. This enables the efficient, directed and regulated handover of ubiquitin from one carrier to the next one. We review some of these conformational transformations, as revealed by crystallographic studies. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 2 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Practitioners (doctors, other healthcare professionals) | 1 | 50% |
| Science communicators (journalists, bloggers, editors) | 1 | 50% |
Mendeley readers
The data shown below were compiled from readership statistics for 83 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 1% |
| Netherlands | 1 | 1% |
| India | 1 | 1% |
| Unknown | 80 | 96% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 24 | 29% |
| Researcher | 14 | 17% |
| Student > Master | 8 | 10% |
| Student > Bachelor | 5 | 6% |
| Other | 4 | 5% |
| Other | 13 | 16% |
| Unknown | 15 | 18% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 28 | 34% |
| Biochemistry, Genetics and Molecular Biology | 22 | 27% |
| Chemistry | 11 | 13% |
| Nursing and Health Professions | 1 | 1% |
| Unspecified | 1 | 1% |
| Other | 4 | 5% |
| Unknown | 16 | 19% |