Title |
MicroR159 regulation of most conserved targets in Arabidopsis has negligible phenotypic effects
|
---|---|
Published in |
Silence, October 2010
|
DOI | 10.1186/1758-907x-1-18 |
Pubmed ID | |
Authors |
Robert S Allen, Junyan Li, Maria M Alonso-Peral, Rosemary G White, Frank Gubler, Anthony A Millar |
Abstract |
A current challenge of microRNA (miRNA) research is the identification of biologically relevant miRNA:target gene relationships. In plants, high miRNA:target gene complementarity has enabled accurate target predictions, and slicing of target mRNAs has facilitated target validation through rapid amplification of 5' cDNA ends (5'-RACE) analysis. Together, these approaches have identified more than 20 targets potentially regulated by the deeply conserved miR159 family in Arabidopsis, including eight MYB genes with highly conserved miR159 target sites. However, genetic analysis has revealed the functional specificity of the major family members, miR159a and miR159b is limited to only two targets, MYB33 and MYB65. Here, we examine the functional role of miR159 regulation for the other potential MYB target genes. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Curaçao | 1 | 50% |
Australia | 1 | 50% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Scientists | 1 | 50% |
Members of the public | 1 | 50% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Portugal | 1 | <1% |
Norway | 1 | <1% |
Argentina | 1 | <1% |
Australia | 1 | <1% |
Unknown | 105 | 96% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 35 | 32% |
Researcher | 25 | 23% |
Student > Master | 14 | 13% |
Student > Bachelor | 7 | 6% |
Student > Doctoral Student | 5 | 5% |
Other | 13 | 12% |
Unknown | 10 | 9% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 75 | 69% |
Biochemistry, Genetics and Molecular Biology | 22 | 20% |
Computer Science | 1 | <1% |
Medicine and Dentistry | 1 | <1% |
Unknown | 10 | 9% |