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Reductions in intestinal Clostridiales precede the development of nosocomial Clostridium difficile infection

Overview of attention for article published in Microbiome, June 2013
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Citations

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Title
Reductions in intestinal Clostridiales precede the development of nosocomial Clostridium difficile infection
Published in
Microbiome, June 2013
DOI 10.1186/2049-2618-1-18
Pubmed ID
Authors

Caroline Vincent, David A Stephens, Vivian G Loo, Thaddeus J Edens, Marcel A Behr, Ken Dewar, Amee R Manges

Abstract

Antimicrobial use is thought to suppress the intestinal microbiota, thereby impairing colonization resistance and allowing Clostridium difficile to infect the gut. Additional risk factors such as proton-pump inhibitors may also alter the intestinal microbiota and predispose patients to Clostridium difficile infection (CDI). This comparative metagenomic study investigates the relationship between epidemiologic exposures, intestinal bacterial populations and subsequent development of CDI in hospitalized patients. We performed a nested case-control study including 25 CDI cases and 25 matched controls. Fecal specimens collected prior to disease onset were evaluated by 16S rRNA gene amplification and pyrosequencing to determine the composition of the intestinal microbiota during the at-risk period.

X Demographics

X Demographics

The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 147 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 2 1%
Ireland 1 <1%
Canada 1 <1%
United Kingdom 1 <1%
Spain 1 <1%
Mexico 1 <1%
Unknown 140 95%

Demographic breakdown

Readers by professional status Count As %
Researcher 32 22%
Student > Ph. D. Student 28 19%
Student > Master 19 13%
Student > Bachelor 12 8%
Other 8 5%
Other 19 13%
Unknown 29 20%
Readers by discipline Count As %
Agricultural and Biological Sciences 40 27%
Medicine and Dentistry 27 18%
Immunology and Microbiology 16 11%
Biochemistry, Genetics and Molecular Biology 15 10%
Environmental Science 4 3%
Other 12 8%
Unknown 33 22%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 27 January 2014.
All research outputs
#15,926,695
of 25,654,806 outputs
Outputs from Microbiome
#1,671
of 1,786 outputs
Outputs of similar age
#118,994
of 208,370 outputs
Outputs of similar age from Microbiome
#7
of 7 outputs
Altmetric has tracked 25,654,806 research outputs across all sources so far. This one is in the 36th percentile – i.e., 36% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,786 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 37.8. This one is in the 5th percentile – i.e., 5% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 208,370 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 41st percentile – i.e., 41% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 7 others from the same source and published within six weeks on either side of this one.