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Transdiagnostic group CBT vs. standard group CBT for depression, social anxiety disorder and agoraphobia/panic disorder: Study protocol for a pragmatic, multicenter non-inferiority randomized…

Overview of attention for article published in BMC Psychiatry, January 2017
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Title
Transdiagnostic group CBT vs. standard group CBT for depression, social anxiety disorder and agoraphobia/panic disorder: Study protocol for a pragmatic, multicenter non-inferiority randomized controlled trial
Published in
BMC Psychiatry, January 2017
DOI 10.1186/s12888-016-1175-0
Pubmed ID
Authors

Sidse M. Arnfred, Ruth Aharoni, Morten Hvenegaard, Stig Poulsen, Bo Bach, Mikkel Arendt, Nicole K. Rosenberg, Nina Reinholt

Abstract

Transdiagnostic Cognitive Behavior Therapy (TCBT) manuals delivered in individual format have been reported to be just as effective as traditional diagnosis specific CBT manuals. We have translated and modified the "The Unified Protocol for Transdiagnostic Treatment of Emotional Disorders" (UP-CBT) for group delivery in Mental Health Service (MHS), and shown effects comparable to traditional CBT in a naturalistic study. As the use of one manual instead of several diagnosis-specific manuals could simplify logistics, reduce waiting time, and increase therapist expertise compared to diagnosis specific CBT, we aim to test the relative efficacy of group UP-CBT and diagnosis specific group CBT. The study is a partially blinded, pragmatic, non-inferiority, parallel, multi-center randomized controlled trial (RCT) of UP-CBT vs diagnosis specific CBT for Unipolar Depression, Social Anxiety Disorder and Agoraphobia/Panic Disorder. In total, 248 patients are recruited from three regional MHS centers across Denmark and included in two intervention arms. The primary outcome is patient-ratings of well-being (WHO Well-being Index, WHO-5), secondary outcomes include level of depressive and anxious symptoms, personality variables, emotion regulation, reflective functioning, and social adjustment. Assessments are conducted before and after therapy and at 6 months follow-up. Weekly patient-rated outcomes and group evaluations are collected for every session. Outcome assessors, blind to treatment allocation, will perform the observer-based symptom ratings, and fidelity assessors will monitor manual adherence. The current study will be the first RCT investigating the dissemination of the UP in a MHS setting, the UP delivered in groups, and with depressive patients included. Hence the results are expected to add substantially to the evidence base for rational group psychotherapy in MHS. The planned moderator and mediator analyses could spur new hypotheses about mechanisms of change in psychotherapy and the association between patient characteristics and treatment effect. Clinicaltrials.gov NCT02954731 . Registered 25 October 2016.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 265 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Colombia 1 <1%
Denmark 1 <1%
Unknown 263 99%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 34 13%
Student > Master 34 13%
Researcher 30 11%
Student > Bachelor 29 11%
Student > Doctoral Student 19 7%
Other 46 17%
Unknown 73 28%
Readers by discipline Count As %
Psychology 113 43%
Medicine and Dentistry 20 8%
Nursing and Health Professions 9 3%
Social Sciences 7 3%
Agricultural and Biological Sciences 5 2%
Other 18 7%
Unknown 93 35%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 28 January 2017.
All research outputs
#20,397,576
of 22,947,506 outputs
Outputs from BMC Psychiatry
#4,244
of 4,723 outputs
Outputs of similar age
#354,718
of 419,069 outputs
Outputs of similar age from BMC Psychiatry
#78
of 82 outputs
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