↓ Skip to main content

A simple strategy for heritable chromosomal deletions in zebrafish via the combinatorial action of targeting nucleases

Overview of attention for article published in Genome Biology, July 2013
Altmetric Badge

About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (88th percentile)
  • Average Attention Score compared to outputs of the same age and source

Mentioned by

news
1 news outlet
twitter
4 X users
googleplus
1 Google+ user

Citations

dimensions_citation
25 Dimensions

Readers on

mendeley
42 Mendeley
citeulike
2 CiteULike
You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output. Click here to find out more.
Title
A simple strategy for heritable chromosomal deletions in zebrafish via the combinatorial action of targeting nucleases
Published in
Genome Biology, July 2013
DOI 10.1186/gb-2013-14-7-r69
Pubmed ID
Authors

Shimin Lim, Yin Wang, Xueyao Yu, Yian Huang, Mark S Featherstone, Karuna Sampath

Abstract

Precise and effective genome-editing tools are essential for functional genomics and gene therapy. Targeting nucleases have been successfully used to edit genomes. However, whole-locus or element-specific deletions abolishing transcript expression have not previously been reported. Here, we show heritable targeting of locus-specific deletions in the zebrafish nodal-related genes squint (sqt) and cyclops (cyc). Our strategy of heritable chromosomal editing can be used for disease modeling, analyzing gene clusters, regulatory regions, and determining the functions of non-coding RNAs in genomes.

X Demographics

X Demographics

The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 42 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 2%
Netherlands 1 2%
Germany 1 2%
Unknown 39 93%

Demographic breakdown

Readers by professional status Count As %
Researcher 11 26%
Student > Bachelor 6 14%
Student > Ph. D. Student 6 14%
Professor > Associate Professor 3 7%
Student > Master 3 7%
Other 7 17%
Unknown 6 14%
Readers by discipline Count As %
Agricultural and Biological Sciences 18 43%
Biochemistry, Genetics and Molecular Biology 12 29%
Computer Science 2 5%
Nursing and Health Professions 1 2%
Medicine and Dentistry 1 2%
Other 1 2%
Unknown 7 17%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 13. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 23 July 2013.
All research outputs
#2,840,304
of 25,374,917 outputs
Outputs from Genome Biology
#2,183
of 4,467 outputs
Outputs of similar age
#23,718
of 206,712 outputs
Outputs of similar age from Genome Biology
#33
of 67 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. Compared to these this one has done well and is in the 88th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 4,467 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 27.6. This one has gotten more attention than average, scoring higher than 51% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 206,712 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 88% of its contemporaries.
We're also able to compare this research output to 67 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 50% of its contemporaries.