↓ Skip to main content

Cidofovir selectivity is based on the different response of normal and cancer cells to DNA damage

Overview of attention for article published in BMC Medical Genomics, May 2013
Altmetric Badge

Readers on

mendeley
34 Mendeley
You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output. Click here to find out more.
Title
Cidofovir selectivity is based on the different response of normal and cancer cells to DNA damage
Published in
BMC Medical Genomics, May 2013
DOI 10.1186/1755-8794-6-18
Pubmed ID
Authors

Tim De Schutter, Graciela Andrei, Dimitri Topalis, Lieve Naesens, Robert Snoeck

Abstract

Cidofovir (CDV) proved efficacious in treatment of human papillomaviruses (HPVs) hyperplasias. Antiproliferative effects of CDV have been associated with apoptosis induction, S-phase accumulation, and increased levels of tumor suppressor proteins. However, the molecular mechanisms for the selectivity and antitumor activity of CDV against HPV-transformed cells remain unexplained.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 34 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Japan 1 3%
Unknown 33 97%

Demographic breakdown

Readers by professional status Count As %
Researcher 6 18%
Student > Bachelor 6 18%
Professor 3 9%
Student > Master 3 9%
Student > Ph. D. Student 3 9%
Other 7 21%
Unknown 6 18%
Readers by discipline Count As %
Medicine and Dentistry 13 38%
Biochemistry, Genetics and Molecular Biology 4 12%
Nursing and Health Professions 2 6%
Agricultural and Biological Sciences 2 6%
Immunology and Microbiology 2 6%
Other 3 9%
Unknown 8 24%