Title |
Shaped Magnetic Field Pulses by Multi-Coil Repetitive Transcranial Magnetic Stimulation (rTMS) Differentially Modulate Anterior Cingulate Cortex Responses and Pain in Volunteers and Fibromyalgia Patients
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Published in |
Molecular Pain, January 2013
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DOI | 10.1186/1744-8069-9-33 |
Pubmed ID | |
Authors |
Alexander Tzabazis, Carina Mari Aparici, Michael C Rowbotham, M Bret Schneider, Amit Etkin, David C Yeomans |
Abstract |
Repetitive transcranial magnetic stimulation (rTMS) has shown promise in the alleviation of acute and chronic pain by altering the activity of cortical areas involved in pain sensation. However, current single-coil rTMS technology only allows for effects in surface cortical structures. The ability to affect activity in certain deep brain structures may however, allow for a better efficacy, safety, and tolerability. This study used PET imaging to determine whether a novel multi-coil rTMS would allow for preferential targeting of the dorsal anterior cingulate cortex (dACC), an area always activated with pain, and to provide preliminary evidence as to whether this targeted approach would allow for efficacious, safe, and tolerable analgesia both in a volunteer/acute pain model as well as in fibromyalgia chronic pain patients. |
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Canada | 1 | 17% |
United Kingdom | 1 | 17% |
Unknown | 2 | 33% |
Demographic breakdown
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Members of the public | 5 | 83% |
Science communicators (journalists, bloggers, editors) | 1 | 17% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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United States | 3 | 2% |
Portugal | 1 | <1% |
Netherlands | 1 | <1% |
Australia | 1 | <1% |
Italy | 1 | <1% |
Spain | 1 | <1% |
Russia | 1 | <1% |
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Student > Ph. D. Student | 20 | 11% |
Student > Master | 18 | 10% |
Other | 14 | 8% |
Other | 36 | 21% |
Unknown | 31 | 18% |
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Neuroscience | 29 | 17% |
Psychology | 22 | 13% |
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Other | 24 | 14% |
Unknown | 37 | 21% |