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New dicoumarol sodium compound: crystal structure, theoretical study and tumoricidal activity against osteoblast cancer cells

Overview of attention for article published in BMC Chemistry, July 2013
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Title
New dicoumarol sodium compound: crystal structure, theoretical study and tumoricidal activity against osteoblast cancer cells
Published in
BMC Chemistry, July 2013
DOI 10.1186/1752-153x-7-110
Pubmed ID
Authors

Sadia Rehman, Muhammad Ikram, Ajmal Khan, Soyoung Min, Effat Azad, Thomas S Hofer, KH Mok, Robert J Baker, Alexander J Blake, Saeed Ur Rehman

Abstract

Enormous interest had been paid to the coordination chemistry of alkali and alkaline metal ions because of their role inside body viz; their Li(+)/Na(+) exchange inside the cell lead to different diseases like neuropathy, hypertension, microalbuminuria, cardiac and vascular hypertrophy, obesity, and insulin resistance. It has been presumed that alkali metal ions (whether Na(+) or K(+)) coordinated to chelating ligands can cross the hydrophobic cell membrane easily and can function effectively for depolarizing the ion difference. This unique function was utilized for bacterial cell death in which K(+) has been found coordinated valinomycin (antibiotic).

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 20 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 20 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 4 20%
Student > Master 2 10%
Student > Bachelor 2 10%
Unspecified 1 5%
Student > Doctoral Student 1 5%
Other 6 30%
Unknown 4 20%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 4 20%
Chemistry 4 20%
Agricultural and Biological Sciences 2 10%
Unspecified 1 5%
Social Sciences 1 5%
Other 3 15%
Unknown 5 25%