Title |
An inducible CiliaGFP mouse model for in vivo visualization and analysis of cilia in live tissue
|
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Published in |
Cilia, July 2013
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DOI | 10.1186/2046-2530-2-8 |
Pubmed ID | |
Authors |
Amber K O’Connor, Erik B Malarkey, Nicolas F Berbari, Mandy J Croyle, Courtney J Haycraft, P Darwin Bell, Peter Hohenstein, Robert A Kesterson, Bradley K Yoder |
Abstract |
Cilia are found on nearly every cell type in the mammalian body, and have been historically classified as either motile or immotile. Motile cilia are important for fluid and cellular movement; however, the roles of non-motile or primary cilia in most tissues remain unknown. Several genetic syndromes, called the ciliopathies, are associated with defects in cilia structure or function and have a wide range of clinical presentations. Much of what we know about the formation and maintenance of cilia comes from model systems like C. elegans and Chalmydomonas. Studies of mammalian cilia in live tissues have been hampered by difficulty visualizing them. |
X Demographics
Geographical breakdown
Country | Count | As % |
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United States | 2 | 40% |
United Kingdom | 2 | 40% |
Unknown | 1 | 20% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 3 | 60% |
Science communicators (journalists, bloggers, editors) | 2 | 40% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 3 | 2% |
United Kingdom | 2 | 2% |
France | 2 | 2% |
Germany | 1 | <1% |
Unknown | 120 | 94% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 33 | 26% |
Researcher | 31 | 24% |
Student > Master | 11 | 9% |
Professor > Associate Professor | 9 | 7% |
Professor | 6 | 5% |
Other | 20 | 16% |
Unknown | 18 | 14% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 45 | 35% |
Biochemistry, Genetics and Molecular Biology | 31 | 24% |
Neuroscience | 11 | 9% |
Medicine and Dentistry | 10 | 8% |
Engineering | 3 | 2% |
Other | 7 | 5% |
Unknown | 21 | 16% |