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Safety, effectiveness, and cost of dipeptidyl peptidase-4 inhibitors versus intermediate acting insulin for type 2 diabetes: protocol for a systematic review and network meta-analysis

Overview of attention for article published in Systematic Reviews, June 2013
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2 X users

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Title
Safety, effectiveness, and cost of dipeptidyl peptidase-4 inhibitors versus intermediate acting insulin for type 2 diabetes: protocol for a systematic review and network meta-analysis
Published in
Systematic Reviews, June 2013
DOI 10.1186/2046-4053-2-47
Pubmed ID
Authors

Andrea C Tricco, Jesmin Antony, Charlene Soobiah, Brenda Hemmelgarn, David Moher, Brian Hutton, Catherine H Yu, Sumit R Majumdar, Sharon E Straus

Abstract

Type 2 diabetes mellitus (T2DM) results from insulin resistance and relative insulin deficiency. T2DM treatment is a step-wise approach beginning with lifestyle modifications (for example, diet, exercise), followed by the addition of oral hypoglycemic agents (for example, metformin). Patients who do not respond to first-line therapy are offered second-line therapy (for example, sulfonylureas). Third-line therapy may include insulin and/or dipeptidyl peptidase-4 (DPP-4) inhibitors.It is unclear whether DPP-4 inhibitors are safer and more effective than intermediate acting insulin for third-line management of T2DM. As such, our objective is to evaluate the comparative effectiveness, safety and cost-effectiveness of DPP-4 inhibitors versus intermediate acting insulin for T2DM patients who have failed both first- and second-line diabetes treatments.

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 119 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Mexico 1 <1%
Ecuador 1 <1%
Unknown 117 98%

Demographic breakdown

Readers by professional status Count As %
Student > Master 22 18%
Student > Bachelor 19 16%
Researcher 17 14%
Student > Ph. D. Student 12 10%
Other 7 6%
Other 23 19%
Unknown 19 16%
Readers by discipline Count As %
Medicine and Dentistry 35 29%
Nursing and Health Professions 11 9%
Economics, Econometrics and Finance 9 8%
Biochemistry, Genetics and Molecular Biology 8 7%
Pharmacology, Toxicology and Pharmaceutical Science 8 7%
Other 23 19%
Unknown 25 21%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 26 November 2013.
All research outputs
#17,690,900
of 22,713,403 outputs
Outputs from Systematic Reviews
#1,698
of 1,987 outputs
Outputs of similar age
#140,495
of 195,446 outputs
Outputs of similar age from Systematic Reviews
#21
of 27 outputs
Altmetric has tracked 22,713,403 research outputs across all sources so far. This one is in the 19th percentile – i.e., 19% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,987 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 12.6. This one is in the 10th percentile – i.e., 10% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 195,446 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 24th percentile – i.e., 24% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 27 others from the same source and published within six weeks on either side of this one. This one is in the 22nd percentile – i.e., 22% of its contemporaries scored the same or lower than it.