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Differential response of BDCA-1+ and BDCA-3+myeloid dendritic cells to respiratory syncytial virus infection

Overview of attention for article published in Respiratory Research, July 2013
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Title
Differential response of BDCA-1+ and BDCA-3+myeloid dendritic cells to respiratory syncytial virus infection
Published in
Respiratory Research, July 2013
DOI 10.1186/1465-9921-14-71
Pubmed ID
Authors

Meera R Gupta, Deepthi Kolli, Roberto P Garofalo

Abstract

Respiratory syncytial virus (RSV) is the leading cause of respiratory infections in children, elderly, and immunocompromised individuals. Severe infection is associated with short- and long-term morbidity including pneumonia, recurrent wheezing, and abnormal pulmonary function, and several lines of evidence indicate that impaired adaptive immune responses during infection are critical in the pathophysiology of RSV-mediated disease. Myeloid Dendritic cells (mDCs) play a pivotal role in shaping antiviral immune responses in the respiratory tract; however, few studies have examined the interactions between RSV and individual mDC subsets. In this study, we examined the effect of RSV on the functional response of primary mDC subsets (BDCA-1(+) and BDCA-3(+)) isolated from peripheral blood.

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The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 36 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 3%
Unknown 35 97%

Demographic breakdown

Readers by professional status Count As %
Researcher 8 22%
Student > Master 6 17%
Other 4 11%
Student > Ph. D. Student 3 8%
Professor > Associate Professor 2 6%
Other 5 14%
Unknown 8 22%
Readers by discipline Count As %
Medicine and Dentistry 9 25%
Agricultural and Biological Sciences 7 19%
Immunology and Microbiology 6 17%
Biochemistry, Genetics and Molecular Biology 2 6%
Pharmacology, Toxicology and Pharmaceutical Science 1 3%
Other 2 6%
Unknown 9 25%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 05 July 2013.
All research outputs
#20,656,820
of 25,374,917 outputs
Outputs from Respiratory Research
#2,702
of 3,062 outputs
Outputs of similar age
#157,289
of 206,624 outputs
Outputs of similar age from Respiratory Research
#15
of 24 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. This one is in the 10th percentile – i.e., 10% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,062 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 7.9. This one is in the 3rd percentile – i.e., 3% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 206,624 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 11th percentile – i.e., 11% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 24 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.