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Implication from thyroid function decreasing during chemotherapy in breast cancer patients: chemosensitization role of triiodothyronine

Overview of attention for article published in BMC Cancer, July 2013
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  • Above-average Attention Score compared to outputs of the same age and source (60th percentile)

Mentioned by

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3 X users
facebook
1 Facebook page

Citations

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49 Dimensions

Readers on

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61 Mendeley
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Title
Implication from thyroid function decreasing during chemotherapy in breast cancer patients: chemosensitization role of triiodothyronine
Published in
BMC Cancer, July 2013
DOI 10.1186/1471-2407-13-334
Pubmed ID
Authors

Jianbo Huang, Liangbin Jin, Guangyan Ji, Lei Xing, Chaobo Xu, Xiong Xiong, Hongyuan Li, Kainan Wu, Guosheng Ren, Lingquan Kong

Abstract

Thyroid hormones have been shown to regulate breast cancer cells growth, the absence or reduction of thyroid hormones in cells could provoke a proliferation arrest in G0-G1 or weak mitochondrial activity, which makes cells insensitive to therapies for cancers through transforming into low metabolism status. This biological phenomenon may help explain why treatment efficacy and prognosis vary among breast cancer patients having hypothyroid, hyperthyroid and normal function. Nevertheless, the abnormal thyroid function in breast cancer patients has been considered being mainly caused by thyroid diseases, few studied influence of chemotherapy on thyroid function and whether its alteration during chemotherapy can influence the respose to chemotherapy is still unclear. So, we aimed to find the alterations of thyroid function and non-thyroidal illness syndrome (NTIS) prevalence druing chemotherapy in breast cancer patients, and investigate the influence of thyroid hormones on chemotherapeutic efficacy.

X Demographics

X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 61 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 2%
Brazil 1 2%
Unknown 59 97%

Demographic breakdown

Readers by professional status Count As %
Researcher 12 20%
Student > Ph. D. Student 8 13%
Student > Bachelor 7 11%
Other 6 10%
Student > Postgraduate 6 10%
Other 8 13%
Unknown 14 23%
Readers by discipline Count As %
Medicine and Dentistry 25 41%
Agricultural and Biological Sciences 7 11%
Biochemistry, Genetics and Molecular Biology 4 7%
Nursing and Health Professions 3 5%
Sports and Recreations 1 2%
Other 2 3%
Unknown 19 31%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 16 July 2013.
All research outputs
#12,878,328
of 22,713,403 outputs
Outputs from BMC Cancer
#2,711
of 8,265 outputs
Outputs of similar age
#98,022
of 194,293 outputs
Outputs of similar age from BMC Cancer
#30
of 75 outputs
Altmetric has tracked 22,713,403 research outputs across all sources so far. This one is in the 42nd percentile – i.e., 42% of other outputs scored the same or lower than it.
So far Altmetric has tracked 8,265 research outputs from this source. They receive a mean Attention Score of 4.3. This one has gotten more attention than average, scoring higher than 66% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 194,293 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 48th percentile – i.e., 48% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 75 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 60% of its contemporaries.