Title |
Rapid assessment of bovine spongiform encephalopathy prion inactivation by heat treatment in yellow grease produced in the industrial manufacturing process of meat and bone meals
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Published in |
BMC Veterinary Research, July 2013
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DOI | 10.1186/1746-6148-9-134 |
Pubmed ID | |
Authors |
Miyako Yoshioka, Yuichi Matsuura, Hiroyuki Okada, Noriko Shimozaki, Tomoaki Yamamura, Yuichi Murayama, Takashi Yokoyama, Shirou Mohri |
Abstract |
Prions, infectious agents associated with transmissible spongiform encephalopathy, are primarily composed of the misfolded and pathogenic form (PrPSc) of the host-encoded prion protein. Because PrPSc retains infectivity after undergoing routine sterilizing processes, the cause of bovine spongiform encephalopathy (BSE) outbreaks are suspected to be feeding cattle meat and bone meals (MBMs) contaminated with the prion. To assess the validity of prion inactivation by heat treatment in yellow grease, which is produced in the industrial manufacturing process of MBMs, we pooled, homogenized, and heat treated the spinal cords of BSE-infected cows under various experimental conditions. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Unknown | 2 | 100% |
Demographic breakdown
Type | Count | As % |
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Practitioners (doctors, other healthcare professionals) | 1 | 50% |
Members of the public | 1 | 50% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 31 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Bachelor | 6 | 19% |
Researcher | 6 | 19% |
Student > Ph. D. Student | 4 | 13% |
Lecturer | 2 | 6% |
Other | 2 | 6% |
Other | 5 | 16% |
Unknown | 6 | 19% |
Readers by discipline | Count | As % |
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Agricultural and Biological Sciences | 10 | 32% |
Biochemistry, Genetics and Molecular Biology | 5 | 16% |
Veterinary Science and Veterinary Medicine | 4 | 13% |
Arts and Humanities | 1 | 3% |
Nursing and Health Professions | 1 | 3% |
Other | 3 | 10% |
Unknown | 7 | 23% |