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Disruption of the blood–brain barrier after generalized tonic-clonic seizures correlates with cerebrospinal fluid MMP-9 levels

Overview of attention for article published in Journal of Neuroinflammation, July 2013
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  • Good Attention Score compared to outputs of the same age and source (66th percentile)

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67 Mendeley
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Title
Disruption of the blood–brain barrier after generalized tonic-clonic seizures correlates with cerebrospinal fluid MMP-9 levels
Published in
Journal of Neuroinflammation, July 2013
DOI 10.1186/1742-2094-10-80
Pubmed ID
Authors

Ya-Jun Li, Zheng-Hai Wang, Bei Zhang, Xiao Zhe, Ming-Jue Wang, Shao-Ting Shi, Jing Bai, Tao Lin, Chang-Jiang Guo, Shi-Jun Zhang, Xiang-Li Kong, Xing Zuo, Hang Zhao

Abstract

Increasing evidence suggests seizures cause blood-brain barrier (BBB) dysfunction including decreased seizure threshold and higher onset potential of future seizures. However, the mechanisms underlying BBB damage in seizures remains poorly understood. Evidence in human and animal models shows BBB disruption is associated with activation of matrix metalloproteinase-9 (MMP-9) after cerebral ischemia and inflammation. The objective of this study was to determine whether MMP-9 concentrations in cerebral spinal fluid (CSF) are associated with BBB disruption in patients after epileptic seizures.

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 67 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Portugal 1 1%
Netherlands 1 1%
Ethiopia 1 1%
Mexico 1 1%
Russia 1 1%
Unknown 62 93%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 17 25%
Researcher 10 15%
Student > Master 9 13%
Unspecified 7 10%
Student > Doctoral Student 5 7%
Other 11 16%
Unknown 8 12%
Readers by discipline Count As %
Agricultural and Biological Sciences 14 21%
Neuroscience 12 18%
Medicine and Dentistry 9 13%
Unspecified 7 10%
Biochemistry, Genetics and Molecular Biology 3 4%
Other 11 16%
Unknown 11 16%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 09 July 2013.
All research outputs
#14,109,611
of 22,713,403 outputs
Outputs from Journal of Neuroinflammation
#1,548
of 2,612 outputs
Outputs of similar age
#108,940
of 194,389 outputs
Outputs of similar age from Journal of Neuroinflammation
#11
of 33 outputs
Altmetric has tracked 22,713,403 research outputs across all sources so far. This one is in the 37th percentile – i.e., 37% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,612 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 7.6. This one is in the 40th percentile – i.e., 40% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 194,389 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 43rd percentile – i.e., 43% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 33 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 66% of its contemporaries.