Title |
Retinoic acid regulates olfactory progenitor cell fate and differentiation
|
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Published in |
Neural Development, July 2013
|
DOI | 10.1186/1749-8104-8-13 |
Pubmed ID | |
Authors |
Marie Paschaki, Laura Cammas, Yuko Muta, Yoko Matsuoka, Siu-Shan Mak, Monika Rataj-Baniowska, Valurie Fraulob, Pascal Dolle, Raj K Ladher |
Abstract |
In order to fulfill their chemosensory function, olfactory neurons are in direct contact with the external environment and are therefore exposed to environmental aggressive factors. Olfaction is maintained through life because, unlike for other sensory neuroepithelia, olfactory neurons have a unique capacity to regenerate after trauma. The mechanisms that control the ontogenesis and regenerative ability of these neurons are not fully understood. Here, we used various experimental approaches in two model systems (chick and mouse) to assess the contribution of retinoic acid signaling in the induction of the olfactory epithelium, the generation and maintenance of progenitor populations, and the ontogenesis and differentiation of olfactory neurons. |
X Demographics
Geographical breakdown
Country | Count | As % |
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India | 1 | 33% |
United Kingdom | 1 | 33% |
Unknown | 1 | 33% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 2 | 67% |
Practitioners (doctors, other healthcare professionals) | 1 | 33% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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India | 1 | 2% |
Germany | 1 | 2% |
Canada | 1 | 2% |
Unknown | 60 | 95% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Ph. D. Student | 16 | 25% |
Student > Master | 9 | 14% |
Professor | 7 | 11% |
Researcher | 7 | 11% |
Student > Bachelor | 5 | 8% |
Other | 7 | 11% |
Unknown | 12 | 19% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 22 | 35% |
Biochemistry, Genetics and Molecular Biology | 14 | 22% |
Neuroscience | 6 | 10% |
Medicine and Dentistry | 4 | 6% |
Unspecified | 1 | 2% |
Other | 2 | 3% |
Unknown | 14 | 22% |