Title |
Life-threatening gastrointestinal bleeding during targeted therapy for advanced renal cell carcinoma: a case report
|
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Published in |
BMC Nephrology, July 2013
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DOI | 10.1186/1471-2369-14-141 |
Pubmed ID | |
Authors |
Shintaro Fujihara, Hirohito Mori, Hideki Kobara, Takehiro Suenaga, Yuji Hayashida, Mikio Sugimoto, Yoshiyuki Kakehi, Tsutomu Masaki |
Abstract |
Temsirolimus has important clinical activity in both untreated and previously treated patients with advanced renal cell carcinoma. Targeted therapy-related stomatitis and mucositis have occurred during targeted therapies, but there is no consensus on which strategy is the most effective. We herein report a case in which several sessions of endoscopic hemostasis with argon plasma coagulation (APC) effectively resolved life-threatening gastrointestinal bleeding that had occurred during targeted therapy. This is the first case report of such an adverse drug reaction in the literature. |
X Demographics
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Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 19 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Ph. D. Student | 4 | 21% |
Researcher | 3 | 16% |
Professor > Associate Professor | 2 | 11% |
Other | 2 | 11% |
Student > Master | 2 | 11% |
Other | 2 | 11% |
Unknown | 4 | 21% |
Readers by discipline | Count | As % |
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Medicine and Dentistry | 10 | 53% |
Economics, Econometrics and Finance | 2 | 11% |
Nursing and Health Professions | 1 | 5% |
Earth and Planetary Sciences | 1 | 5% |
Unknown | 5 | 26% |