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Genes and primary headaches: discovering new potential therapeutic targets

Overview of attention for article published in The Journal of Headache and Pain, July 2013
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  • Above-average Attention Score compared to outputs of the same age and source (56th percentile)

Mentioned by

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3 X users
facebook
3 Facebook pages

Citations

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15 Dimensions

Readers on

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32 Mendeley
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Title
Genes and primary headaches: discovering new potential therapeutic targets
Published in
The Journal of Headache and Pain, July 2013
DOI 10.1186/1129-2377-14-61
Pubmed ID
Authors

Innocenzo Rainero, Elisa Rubino, Koen Paemeleire, Annalisa Gai, Alessandro Vacca, Paola De Martino, Salvatore Gentile, Paola Sarchielli, Lorenzo Pinessi

Abstract

Genetic studies have clearly shown that primary headaches (migraine, tension-type headache and cluster headache) are multifactorial disorders characterized by a complex interaction between different genes and environmental factors. Genetic association studies have highlighted a potential role in the etiopathogenesis of these disorders for several genes related to vascular, neuronal and neuroendocrine functions. A potential role as a therapeutic target is now emerging for some of these genes. The main purpose of this review is to describe new advances in our knowledge regarding the role of MTHFR, KCNK18, TRPV1, TRPV3 and HCRTR genes in primary headache disorders. Involvement of these genes in primary headaches, as well as their potential role in the therapy of these disorders, will be discussed.

X Demographics

X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 32 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Japan 1 3%
United Kingdom 1 3%
Unknown 30 94%

Demographic breakdown

Readers by professional status Count As %
Student > Master 5 16%
Other 5 16%
Researcher 5 16%
Student > Bachelor 4 13%
Student > Ph. D. Student 3 9%
Other 6 19%
Unknown 4 13%
Readers by discipline Count As %
Medicine and Dentistry 11 34%
Agricultural and Biological Sciences 5 16%
Neuroscience 3 9%
Nursing and Health Professions 2 6%
Biochemistry, Genetics and Molecular Biology 1 3%
Other 2 6%
Unknown 8 25%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 14 December 2014.
All research outputs
#13,345,950
of 23,849,058 outputs
Outputs from The Journal of Headache and Pain
#836
of 1,417 outputs
Outputs of similar age
#99,296
of 196,863 outputs
Outputs of similar age from The Journal of Headache and Pain
#10
of 23 outputs
Altmetric has tracked 23,849,058 research outputs across all sources so far. This one is in the 43rd percentile – i.e., 43% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,417 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 17.6. This one is in the 40th percentile – i.e., 40% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 196,863 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 49th percentile – i.e., 49% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 23 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 56% of its contemporaries.