Title |
Lymphoepithelial-like carcinoma of the parotid gland: a case report and a brief review of the western literature
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Published in |
Diagnostic Pathology, July 2013
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DOI | 10.1186/1746-1596-8-115 |
Pubmed ID | |
Authors |
Maria R Ambrosio, Maria G Mastrogiulio, Aurora Barone, Bruno J Rocca, Carmine Gallo, Stefano Lazzi, Lorenzo Leoncini, Cristiana Bellan |
Abstract |
Primary lymphoepithelial-like carcinoma of the parotid gland is a rare tumour with an increased incidence among Eskimos and Orientals. In these populations, it is usually associated with Epstein-Barr virus. In Western countries, salivary gland lymphoepithelial-like carcinoma are uncommon and only 14 cases have been described so far; among these, only three cases showed Epstein-Barr virus positivity.Case report: A 45-year-old woman was admitted to Siena Hospital for evaluation of a pre-existent (2 years) painless and tender submandibular mass, rapidly enlarging since two months. On physical examination, a 2.5-cm mass was found in the right parotid. It was firm, mobile and non-tender. Laboratory data were within reference range. Nuclear magnetic resonance detected a 2,5x1,5x1-cm well-circumscribed mass in the deep lobe of the right parotid. A right total paroditectomy with dissection of a satellite lymph node was performed. On the basis of morphological, immunohistochemical and molecular biology findings, a diagnosis of stage II (according to TNM7) Epstein Barr-virus positive, undifferentiated lymphoepithelial-like carcinoma of the parotid gland was made. Twenty months after surgery she was free of disease. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 28 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Postgraduate | 6 | 21% |
Student > Master | 4 | 14% |
Other | 4 | 14% |
Lecturer | 3 | 11% |
Student > Doctoral Student | 2 | 7% |
Other | 6 | 21% |
Unknown | 3 | 11% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 19 | 68% |
Unspecified | 1 | 4% |
Computer Science | 1 | 4% |
Biochemistry, Genetics and Molecular Biology | 1 | 4% |
Physics and Astronomy | 1 | 4% |
Other | 1 | 4% |
Unknown | 4 | 14% |