Title |
Measuring thyroid peroxidase antibodies on the day nulliparous women present for management of miscarriage: a descriptive cohort study
|
---|---|
Published in |
Reproductive Biology and Endocrinology, May 2013
|
DOI | 10.1186/1477-7827-11-40 |
Pubmed ID | |
Authors |
Mathis Grossmann, Rudolf Hoermann, Claire Francis, Emma J Hamilton, Aye Tint, Tu’uhevaha Kaitu’u-Lino, Kent Kuswanto, Martha Lappas, Ken Sikaris, Jeffery D Zajac, Michael Permezel, Stephen Tong |
Abstract |
There has been recent evidence suggesting the presence of anti-thyroid peroxidase antibodies (TPOAb) increases the risk of miscarriage, and levothyroxine can rescue miscarriages associated with TPOAb. We propose the most clinically pragmatic cohort to screen for TPOAb are women presenting for management of a missed miscarriage and have never birthed a liveborn. We measured serum TPOAb among nulliparous women presenting for management of miscarriage, and compared levels with women who have had 2 or more livebirths (and never miscarried). Given its potential role in immunomodulation, we also measured Vitamin D levels. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 1 | 50% |
Unknown | 1 | 50% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 2 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 29 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 5 | 17% |
Other | 3 | 10% |
Student > Master | 3 | 10% |
Student > Bachelor | 2 | 7% |
Unspecified | 2 | 7% |
Other | 8 | 28% |
Unknown | 6 | 21% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 13 | 45% |
Unspecified | 2 | 7% |
Business, Management and Accounting | 2 | 7% |
Agricultural and Biological Sciences | 2 | 7% |
Nursing and Health Professions | 1 | 3% |
Other | 2 | 7% |
Unknown | 7 | 24% |