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Oral intake of phenylbutyrate with or without vitamin D3upregulates the cathelicidin LL-37 in human macrophages: a dose finding study for treatment of tuberculosis

Overview of attention for article published in BMC Pulmonary Medicine, April 2013
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2 X users
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1 Facebook page

Citations

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78 Dimensions

Readers on

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118 Mendeley
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Title
Oral intake of phenylbutyrate with or without vitamin D3upregulates the cathelicidin LL-37 in human macrophages: a dose finding study for treatment of tuberculosis
Published in
BMC Pulmonary Medicine, April 2013
DOI 10.1186/1471-2466-13-23
Pubmed ID
Authors

Akhirunnesa Mily, Rokeya Sultana Rekha, S M Mostafa Kamal, Evana Akhtar, Protim Sarker, Zeaur Rahim, Gudmundur H Gudmundsson, Birgitta Agerberth, Rubhana Raqib

Abstract

We earlier showed that 4-phenylbutyrate (PB) can induce cathelicidin LL-37 expression synergistically with 1,25-dihydroxyvitamin D3 in a lung epithelial cell line. We aimed to evaluate a therapeutic dose of PB alone or in combination with vitamin D3 for induction of LL-37 expression in immune cells and enhancement of antimycobacterial activity in monocyte-derived macrophages (MDM).

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 118 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Colombia 1 <1%
France 1 <1%
Sweden 1 <1%
South Africa 1 <1%
Mexico 1 <1%
Unknown 113 96%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 20 17%
Student > Bachelor 15 13%
Researcher 14 12%
Student > Master 9 8%
Student > Doctoral Student 7 6%
Other 26 22%
Unknown 27 23%
Readers by discipline Count As %
Medicine and Dentistry 23 19%
Agricultural and Biological Sciences 19 16%
Biochemistry, Genetics and Molecular Biology 14 12%
Immunology and Microbiology 11 9%
Pharmacology, Toxicology and Pharmaceutical Science 5 4%
Other 15 13%
Unknown 31 26%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 16 September 2021.
All research outputs
#14,755,656
of 22,714,025 outputs
Outputs from BMC Pulmonary Medicine
#953
of 1,899 outputs
Outputs of similar age
#105,223
of 175,243 outputs
Outputs of similar age from BMC Pulmonary Medicine
#13
of 20 outputs
Altmetric has tracked 22,714,025 research outputs across all sources so far. This one is in the 32nd percentile – i.e., 32% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,899 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.4. This one is in the 43rd percentile – i.e., 43% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 175,243 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 37th percentile – i.e., 37% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 20 others from the same source and published within six weeks on either side of this one. This one is in the 35th percentile – i.e., 35% of its contemporaries scored the same or lower than it.