Title |
Portuguese propolis disturbs glycolytic metabolism of human colorectal cancer in vitro
|
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Published in |
BMC Complementary Medicine and Therapies, July 2013
|
DOI | 10.1186/1472-6882-13-184 |
Pubmed ID | |
Authors |
Isabel Valença, Filipa Morais-Santos, Vera Miranda-Gonçalves, Ana Margarida Ferreira, Cristina Almeida-Aguiar, Fátima Baltazar |
Abstract |
Propolis is a resin collected by bees from plant buds and exudates, which is further processed through the activity of bee enzymes. Propolis has been shown to possess many biological and pharmacological properties, such as antimicrobial, antioxidant, immunostimulant and antitumor activities. Due to this bioactivity profile, this resin can become an alternative, economic and safe source of natural bioactive compounds.Antitumor action has been reported in vitro and in vivo for propolis extracts or its isolated compounds; however, Portuguese propolis has been little explored. The aim of this work was to evaluate the in vitro antitumor activity of Portuguese propolis on the human colon carcinoma cell line HCT-15, assessing the effect of different fractions (hexane, chloroform and ethanol residual) of a propolis ethanol extract on cell viability, proliferation, metabolism and death. |
X Demographics
Geographical breakdown
Country | Count | As % |
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United States | 2 | 67% |
Unknown | 1 | 33% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 3 | 100% |
Mendeley readers
Geographical breakdown
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India | 1 | 2% |
Sweden | 1 | 2% |
Denmark | 1 | 2% |
Unknown | 59 | 95% |
Demographic breakdown
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Student > Master | 10 | 16% |
Student > Bachelor | 7 | 11% |
Student > Doctoral Student | 4 | 6% |
Other | 4 | 6% |
Other | 16 | 26% |
Unknown | 9 | 15% |
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Biochemistry, Genetics and Molecular Biology | 8 | 13% |
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Medicine and Dentistry | 3 | 5% |
Other | 8 | 13% |
Unknown | 15 | 24% |