Title |
Glomerular Filtration Rate (GFR) determination via individual kinetics of the inulin-like polyfructosan sinistrin versus creatinine-based population-derived regression formulae
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Published in |
BMC Nephrology, July 2013
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DOI | 10.1186/1471-2369-14-159 |
Pubmed ID | |
Authors |
Sabine Zitta, Walter Schrabmair, Gilbert Reibnegger, Andreas Meinitzer, Doris Wagner, Willibald Estelberger, Alexander R Rosenkranz |
Abstract |
In renal patients estimation of GFR is routinely done by means of population-based formulae using serum creatinine levels. For GFR determination in the creatinine-blind regions or in cases of reno-hepatic syndrome as well as in critical cases of live kidney donors individualized measurements of GFR (mGFR) employing the kinetics of exogenous filtration markers such as the inulin-like polyfructosan sinistrin are necessary. The goal of this study is to compare mGFR values with the eGFR values gained by the Modification of Diet in Renal Disease (MDRD4) and Chronic Kidney Disease-Epidemiology Collaboration (CKD-EPI) formulae. |
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