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Molecular evidence of Plasmodium vivax infection in Duffy negative symptomatic individuals from Dschang, West Cameroon

Overview of attention for article published in Malaria Journal, February 2017
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  • In the top 25% of all research outputs scored by Altmetric
  • Good Attention Score compared to outputs of the same age (76th percentile)
  • High Attention Score compared to outputs of the same age and source (81st percentile)

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Title
Molecular evidence of Plasmodium vivax infection in Duffy negative symptomatic individuals from Dschang, West Cameroon
Published in
Malaria Journal, February 2017
DOI 10.1186/s12936-017-1722-2
Pubmed ID
Authors

Gianluca Russo, Giovanni Faggioni, Giacomo Maria Paganotti, Ghyslaine Bruna Djeunang Dongho, Alice Pomponi, Riccardo De Santis, Gianpiero Tebano, Mpoame Mbida, Martin Sanou Sobze, Vincenzo Vullo, Giovanni Rezza, Florigio Romano Lista

Abstract

Plasmodium vivax infection is known to be rare in West/Central Africa, the most accepted explanation being the lack of expression of erythroid Duffy antigen in the local human populations. Duffy negativity prevents the parasite to exploit the entry mechanism on the red blood cell surface. However, there are a growing number of reported vivax infections in Duffy-negative individuals. Data on P. vivax circulation in Cameroon are limited. The aim of the study was to evaluate the P. vivax presence, and its association with the Duffy genotype in West Cameroon. Overall, 484 blood samples were collected consecutively from febrile outpatients attending the Dschang's Hospital (West Cameroon) during a 3-months period. Plasmodium vivax infection was detected by PCR in 5.6% (n = 27/484) of the cases, representing 38.6% (n = 27/70) of all Plasmodium infections detected. All P. vivax infected individuals showed a Duffy-negative genotype, and the frequency of Duffy-positive individuals in the whole tested population was 1.7%. The results of this study confirm the circulation of P. vivax in Cameroon, as well as that the lack of expression of Duffy-antigen does not confer full protection against vivax malaria acquisition.

X Demographics

X Demographics

The data shown below were collected from the profiles of 11 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 101 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 101 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 18 18%
Student > Master 16 16%
Student > Bachelor 12 12%
Researcher 11 11%
Student > Doctoral Student 6 6%
Other 12 12%
Unknown 26 26%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 18 18%
Medicine and Dentistry 17 17%
Agricultural and Biological Sciences 17 17%
Immunology and Microbiology 8 8%
Social Sciences 3 3%
Other 8 8%
Unknown 30 30%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 7. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 21 February 2017.
All research outputs
#4,948,232
of 24,380,741 outputs
Outputs from Malaria Journal
#1,225
of 5,820 outputs
Outputs of similar age
#100,100
of 436,367 outputs
Outputs of similar age from Malaria Journal
#25
of 129 outputs
Altmetric has tracked 24,380,741 research outputs across all sources so far. Compared to these this one has done well and is in the 79th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 5,820 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 7.0. This one has done well, scoring higher than 78% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 436,367 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 76% of its contemporaries.
We're also able to compare this research output to 129 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 81% of its contemporaries.