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Ecrg4 expression and its product augurin in the choroid plexus: impact on fetal brain development, cerebrospinal fluid homeostasis and neuroprogenitor cell response to CNS injury

Overview of attention for article published in Fluids and Barriers of the CNS, January 2011
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Title
Ecrg4 expression and its product augurin in the choroid plexus: impact on fetal brain development, cerebrospinal fluid homeostasis and neuroprogenitor cell response to CNS injury
Published in
Fluids and Barriers of the CNS, January 2011
DOI 10.1186/2045-8118-8-6
Pubmed ID
Authors

Ana Maria Gonzalez, Sonia Podvin, Shuh-Yow Lin, Miles C Miller, Hannah Botfield, Wendy E Leadbeater, Andrew Roberton, Xitong Dang, Stuart E Knowling, Elena Cardenas-Galindo, John E Donahue, Edward G Stopa, Conrad E Johanson, Raul Coimbra, Brian P Eliceiri, Andrew Baird

Abstract

The content and composition of cerebrospinal fluid (CSF) is determined in large part by the choroid plexus (CP) and specifically, a specialized epithelial cell (CPe) layer that responds to, synthesizes, and transports peptide hormones into and out of CSF. Together with ventricular ependymal cells, these CPe relay homeostatic signals throughout the central nervous system (CNS) and regulate CSF hydrodynamics. One new candidate signal is augurin, a newly recognized 14 kDa protein that is encoded by esophageal cancer related gene-4 (Ecrg4), a putative tumor suppressor gene whose presence and function in normal tissues remains unexplored and enigmatic. The aim of this study was to explore whether Ecrg4 and its product augurin, can be implicated in CNS development and the response to CNS injury.

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The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 45 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Portugal 1 2%
Unknown 44 98%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 8 18%
Student > Master 7 16%
Professor 6 13%
Professor > Associate Professor 5 11%
Student > Bachelor 2 4%
Other 8 18%
Unknown 9 20%
Readers by discipline Count As %
Medicine and Dentistry 10 22%
Agricultural and Biological Sciences 9 20%
Biochemistry, Genetics and Molecular Biology 6 13%
Neuroscience 4 9%
Immunology and Microbiology 2 4%
Other 3 7%
Unknown 11 24%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 10 August 2013.
All research outputs
#15,274,524
of 22,714,025 outputs
Outputs from Fluids and Barriers of the CNS
#219
of 358 outputs
Outputs of similar age
#141,298
of 182,111 outputs
Outputs of similar age from Fluids and Barriers of the CNS
#8
of 9 outputs
Altmetric has tracked 22,714,025 research outputs across all sources so far. This one is in the 22nd percentile – i.e., 22% of other outputs scored the same or lower than it.
So far Altmetric has tracked 358 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.2. This one is in the 28th percentile – i.e., 28% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 182,111 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 12th percentile – i.e., 12% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 9 others from the same source and published within six weeks on either side of this one.