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Resolving breast cancer heterogeneity by searching reliable protein cancer biomarkers in the breast fluid secretome

Overview of attention for article published in BMC Cancer, July 2013
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (83rd percentile)
  • High Attention Score compared to outputs of the same age and source (88th percentile)

Mentioned by

blogs
1 blog
twitter
1 X user
facebook
1 Facebook page

Readers on

mendeley
56 Mendeley
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Title
Resolving breast cancer heterogeneity by searching reliable protein cancer biomarkers in the breast fluid secretome
Published in
BMC Cancer, July 2013
DOI 10.1186/1471-2407-13-344
Pubmed ID
Authors

Ferdinando Mannello, Daniela Ligi

Abstract

One of the major goals in cancer research is to find and evaluate the early presence of biomarkers in human fluids and tissues. To resolve the complex cell heterogeneity of a tumor mass, it will be useful to characterize the intricate biomolecular composition of tumor microenvironment (the so called cancer secretome), validating secreted proteins as early biomarkers of cancer initiation and progression. This approach is not broadly applicable because of the paucity of well validated and FDA-approved biomarkers and because most of the candidate biomarkers are mainly organ-specific rather than tumor-specific. For these reasons, there is an urgent need to identify and validate a panel of biomarker combinations for early detection of human tumors. This is especially important for breast cancer, the cancer spread most worldwide among women. It is well known that patients with early diagnosed breast cancer live longer, require less extensive treatment and fare better than patients with more aggressive and/or advanced disease.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 56 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
India 1 2%
Korea, Republic of 1 2%
Unknown 54 96%

Demographic breakdown

Readers by professional status Count As %
Researcher 14 25%
Student > Ph. D. Student 10 18%
Student > Master 10 18%
Student > Bachelor 4 7%
Student > Doctoral Student 3 5%
Other 9 16%
Unknown 6 11%
Readers by discipline Count As %
Medicine and Dentistry 13 23%
Biochemistry, Genetics and Molecular Biology 10 18%
Agricultural and Biological Sciences 10 18%
Engineering 4 7%
Chemistry 3 5%
Other 3 5%
Unknown 13 23%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 9. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 06 August 2013.
All research outputs
#3,718,917
of 22,714,025 outputs
Outputs from BMC Cancer
#877
of 8,265 outputs
Outputs of similar age
#32,132
of 194,568 outputs
Outputs of similar age from BMC Cancer
#8
of 70 outputs
Altmetric has tracked 22,714,025 research outputs across all sources so far. Compared to these this one has done well and is in the 83rd percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 8,265 research outputs from this source. They receive a mean Attention Score of 4.3. This one has done well, scoring higher than 89% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 194,568 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 83% of its contemporaries.
We're also able to compare this research output to 70 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 88% of its contemporaries.