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Increase of urinary malondialdehyde level by bisphenol A exposure: a longitudinal panel study

Overview of attention for article published in Environmental Health, February 2017
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Title
Increase of urinary malondialdehyde level by bisphenol A exposure: a longitudinal panel study
Published in
Environmental Health, February 2017
DOI 10.1186/s12940-017-0221-9
Pubmed ID
Authors

Jin Hee Kim, Yun-Chul Hong

Abstract

To verify oxidative stress as a possible mechanism that establishes a relationship between exposure to bisphenol A (BPA) and adverse health outcomes in the elderly Korean population, we evaluated the relation between visit-to-visit variations in urinary BPA and oxidative stress biomarker. To assess the relation between BPA and urinary malondialdehyde (MDA) as an oxidative stress biomarker, we used a mixed effect model after controlling for age, sex, BMI, drinking status, exercise, urinary cotinine level, PM10 on lag day 2, and mean temperature and dew point on the day. The relation between exposure to BPA and MDA level by sex of participants and polymorphisms of oxidative stress-related genes (COX2, EPHX1, HSP70-hom, PON1, eNOS, CAT, DRD2, SOD2, and MPO) was also evaluated. A significant association was found for BPA with MDA in both male and female elderly participants (male, β = 0.19 and p = 0.0003; female, β = 0.18 and p < .0001; and total, β = 0.18 and p < .0001). Furthermore, the association of BPA with MDA was found regardless of any genotype of the nine oxidative stress-related genes. The results of our study suggest a strong association of BPA with oxidative stress, not related with sex and oxidative stress-related gene polymorphisms.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 42 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 42 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 8 19%
Student > Bachelor 7 17%
Student > Master 3 7%
Student > Doctoral Student 2 5%
Researcher 2 5%
Other 7 17%
Unknown 13 31%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 5 12%
Nursing and Health Professions 5 12%
Agricultural and Biological Sciences 4 10%
Medicine and Dentistry 4 10%
Environmental Science 3 7%
Other 5 12%
Unknown 16 38%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 15 February 2017.
All research outputs
#20,403,545
of 22,953,506 outputs
Outputs from Environmental Health
#1,348
of 1,498 outputs
Outputs of similar age
#385,154
of 454,358 outputs
Outputs of similar age from Environmental Health
#27
of 31 outputs
Altmetric has tracked 22,953,506 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
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