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Intrinsic disorder in putative protein sequences

Overview of attention for article published in Proteome Science, June 2012
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Title
Intrinsic disorder in putative protein sequences
Published in
Proteome Science, June 2012
DOI 10.1186/1477-5956-10-s1-s19
Pubmed ID
Authors

Uros Midic, Zoran Obradovic

Abstract

Intrinsically disordered proteins (IDPs) and regions (IDRs) perform a variety of crucial biological functions despite lacking stable tertiary structure under physiological conditions in vitro. State-of-the-art sequence-based predictors of intrinsic disorder are achieving per-residue accuracies over 80%. In a genome-wide study of intrinsic disorder in human genome we observed a big difference in predicted disorder content between confirmed and putative human proteins. We investigated a hypothesis that this discrepancy is not correct, and that it is due to incorrectly annotated parts of the putative protein sequences that exhibit some similarities to confirmed IDRs, which lead to high predicted disorder content.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 12 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 8%
Poland 1 8%
Unknown 10 83%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 5 42%
Researcher 3 25%
Student > Doctoral Student 1 8%
Unknown 3 25%
Readers by discipline Count As %
Agricultural and Biological Sciences 3 25%
Medicine and Dentistry 2 17%
Nursing and Health Professions 1 8%
Biochemistry, Genetics and Molecular Biology 1 8%
Psychology 1 8%
Other 1 8%
Unknown 3 25%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 23 May 2013.
All research outputs
#17,286,645
of 25,374,917 outputs
Outputs from Proteome Science
#114
of 208 outputs
Outputs of similar age
#116,621
of 177,443 outputs
Outputs of similar age from Proteome Science
#1
of 5 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. This one is in the 21st percentile – i.e., 21% of other outputs scored the same or lower than it.
So far Altmetric has tracked 208 research outputs from this source. They receive a mean Attention Score of 2.8. This one is in the 33rd percentile – i.e., 33% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 177,443 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 24th percentile – i.e., 24% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 5 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them