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Introduction of the AmpliChip CYP450 Test to a South African cohort: a platform comparative prospective cohort study

Overview of attention for article published in BMC Medical Genomics, January 2013
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Citations

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Title
Introduction of the AmpliChip CYP450 Test to a South African cohort: a platform comparative prospective cohort study
Published in
BMC Medical Genomics, January 2013
DOI 10.1186/1471-2350-14-20
Pubmed ID
Authors

Tyren M Dodgen, Warren E Hochfeld, Heidi Fickl, Sahle M Asfaha, Chrisna Durandt, Paul Rheeder, Britt I Drögemöller, Galen E B Wright, Louise Warnich, Christiaan DJ Labuschagne, Antoinette van Schalkwyk, Andrea Gaedigk, Michael S Pepper

Abstract

Adverse drug reactions and lack of therapeutic efficacy associated with currently prescribed pharmacotherapeutics may be attributed, in part, to inter-individual variability in drug metabolism. Studies on the pharmacogenetics of Cytochrome P450 (CYP) enzymes offer insight into this variability. The objective of this study was to compare the AmpliChip CYP450 Test® (AmpliChip) to alternative genotyping platforms for phenotype prediction of CYP2C19 and CYP2D6 in a representative cohort of the South African population.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 72 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
South Africa 3 4%
Italy 1 1%
Thailand 1 1%
Brazil 1 1%
Unknown 66 92%

Demographic breakdown

Readers by professional status Count As %
Student > Master 14 19%
Researcher 13 18%
Student > Ph. D. Student 11 15%
Student > Bachelor 6 8%
Other 6 8%
Other 14 19%
Unknown 8 11%
Readers by discipline Count As %
Agricultural and Biological Sciences 25 35%
Biochemistry, Genetics and Molecular Biology 20 28%
Medicine and Dentistry 7 10%
Pharmacology, Toxicology and Pharmaceutical Science 4 6%
Computer Science 1 1%
Other 4 6%
Unknown 11 15%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 26 June 2013.
All research outputs
#17,286,379
of 25,374,917 outputs
Outputs from BMC Medical Genomics
#1,315
of 2,444 outputs
Outputs of similar age
#193,759
of 290,753 outputs
Outputs of similar age from BMC Medical Genomics
#18
of 31 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. This one is in the 21st percentile – i.e., 21% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,444 research outputs from this source. They receive a mean Attention Score of 4.4. This one is in the 36th percentile – i.e., 36% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 290,753 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 23rd percentile – i.e., 23% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 31 others from the same source and published within six weeks on either side of this one. This one is in the 25th percentile – i.e., 25% of its contemporaries scored the same or lower than it.