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Changes in codon-pair bias of human immunodeficiency virus type 1 have profound effects on virus replication in cell culture

Overview of attention for article published in Retrovirology, July 2013
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Title
Changes in codon-pair bias of human immunodeficiency virus type 1 have profound effects on virus replication in cell culture
Published in
Retrovirology, July 2013
DOI 10.1186/1742-4690-10-78
Pubmed ID
Authors

Gloria Martrus, Maria Nevot, Cristina Andres, Bonaventura Clotet, Miguel Angel Martinez

Abstract

Human immunodeficiency virus type 1 (HIV-1) has a biased nucleotide composition different from human genes. This raises the question of how evolution has chosen the nucleotide sequence of HIV-1 that is observed today, or to what extent the actual encoding contributes to virus replication capacity, evolvability and pathogenesis. Here, we applied the previously described synthetic attenuated virus engineering (SAVE) approach to HIV-1.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 76 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 1%
Unknown 75 99%

Demographic breakdown

Readers by professional status Count As %
Researcher 20 26%
Student > Ph. D. Student 13 17%
Student > Master 10 13%
Student > Doctoral Student 6 8%
Student > Bachelor 5 7%
Other 8 11%
Unknown 14 18%
Readers by discipline Count As %
Agricultural and Biological Sciences 24 32%
Biochemistry, Genetics and Molecular Biology 15 20%
Immunology and Microbiology 9 12%
Medicine and Dentistry 4 5%
Mathematics 2 3%
Other 6 8%
Unknown 16 21%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 26 July 2013.
All research outputs
#20,674,485
of 25,394,764 outputs
Outputs from Retrovirology
#1,079
of 1,273 outputs
Outputs of similar age
#159,747
of 210,055 outputs
Outputs of similar age from Retrovirology
#17
of 23 outputs
Altmetric has tracked 25,394,764 research outputs across all sources so far. This one is in the 10th percentile – i.e., 10% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,273 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.7. This one is in the 4th percentile – i.e., 4% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 210,055 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 10th percentile – i.e., 10% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 23 others from the same source and published within six weeks on either side of this one. This one is in the 13th percentile – i.e., 13% of its contemporaries scored the same or lower than it.