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HTR4 gene structure and altered expression in the developing lung

Overview of attention for article published in Respiratory Research, July 2013
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Title
HTR4 gene structure and altered expression in the developing lung
Published in
Respiratory Research, July 2013
DOI 10.1186/1465-9921-14-77
Pubmed ID
Authors

Emily Hodge, Carl P Nelson, Suzanne Miller, Charlotte K Billington, Ceri E Stewart, Caroline Swan, Anders Malarstig, Amanda P Henry, Catherine Gowland, Erik Melén, Ian P Hall, Ian Sayers

Abstract

Meta-analyses of genome-wide association studies (GWAS) have identified single nucleotide polymorphisms (SNPs) spanning the 5-hydroxytryptamine receptor 4 (5-HT₄R) gene (HTR4) associated with lung function. The aims of this study were to i) investigate the expression profile of HTR4 in adult and fetal lung tissue and cultured airway cells, ii) further define HTR4 gene structure and iii) explore the potential functional implications of key SNPs using a bioinformatic approach.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 37 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Sweden 1 3%
Portugal 1 3%
Germany 1 3%
Unknown 34 92%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 7 19%
Researcher 5 14%
Student > Postgraduate 4 11%
Student > Bachelor 3 8%
Professor > Associate Professor 2 5%
Other 8 22%
Unknown 8 22%
Readers by discipline Count As %
Medicine and Dentistry 9 24%
Biochemistry, Genetics and Molecular Biology 7 19%
Agricultural and Biological Sciences 4 11%
Neuroscience 2 5%
Environmental Science 2 5%
Other 3 8%
Unknown 10 27%