↓ Skip to main content

The immunogenicity to the first anti-TNF therapy determines the outcome of switching to a second anti-TNF therapy in spondyloarthritis patients

Overview of attention for article published in Arthritis Research & Therapy, July 2013
Altmetric Badge

Mentioned by

twitter
1 X user

Citations

dimensions_citation
62 Dimensions

Readers on

mendeley
67 Mendeley
You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output. Click here to find out more.
Title
The immunogenicity to the first anti-TNF therapy determines the outcome of switching to a second anti-TNF therapy in spondyloarthritis patients
Published in
Arthritis Research & Therapy, July 2013
DOI 10.1186/ar4258
Pubmed ID
Authors

Chamaida Plasencia, Dora Pascual-Salcedo, Sara García-Carazo, Leticia Lojo, Laura Nuño, Alejandro Villalba, Diana Peiteado, Florencia Arribas, Jesus Díez, Maria Teresa López-Casla, Emilio Martín-Mola, Alejandro Balsa

Abstract

Anti-TNF drugs have proven to be effective against spondyloarthritis (SpA), although 30% of patients fail to respond or experience adverse events leading to treatment discontinuation. In rheumatoid arthritis, the presence of anti-drug antibodies (ADA) against the first TNF inhibitor influences the outcome after switching. Our aim was to assess whether the response to a second anti-TNF drug is related to the previous development of ADA to the first anti-TNF drug SpA patients.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 67 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Germany 2 3%
United Kingdom 1 1%
Unknown 64 96%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 13 19%
Researcher 9 13%
Student > Master 8 12%
Student > Doctoral Student 8 12%
Other 4 6%
Other 13 19%
Unknown 12 18%
Readers by discipline Count As %
Medicine and Dentistry 27 40%
Agricultural and Biological Sciences 9 13%
Pharmacology, Toxicology and Pharmaceutical Science 5 7%
Biochemistry, Genetics and Molecular Biology 4 6%
Nursing and Health Professions 3 4%
Other 6 9%
Unknown 13 19%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 29 July 2013.
All research outputs
#20,655,686
of 25,383,344 outputs
Outputs from Arthritis Research & Therapy
#2,891
of 3,361 outputs
Outputs of similar age
#159,559
of 210,001 outputs
Outputs of similar age from Arthritis Research & Therapy
#27
of 31 outputs
Altmetric has tracked 25,383,344 research outputs across all sources so far. This one is in the 10th percentile – i.e., 10% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,361 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.0. This one is in the 7th percentile – i.e., 7% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 210,001 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 10th percentile – i.e., 10% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 31 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.