Title |
Analyses of chondrogenic induction of adipose mesenchymal stem cells by combined co-stimulation mediated by adenoviral gene transfer
|
---|---|
Published in |
Arthritis Research & Therapy, July 2013
|
DOI | 10.1186/ar4260 |
Pubmed ID | |
Authors |
Idalia Garza-Veloz, Viktor J Romero-Diaz, Margarita L Martinez-Fierro, Ivan A Marino-Martinez, Manuel Gonzalez-Rodriguez, Herminia G Martinez-Rodriguez, Marcela A Espinoza-Juarez, Dante A Bernal-Garza, Rocio Ortiz-Lopez, Augusto Rojas-Martinez |
Abstract |
Adipose-derived stem cells (ASCs) have the potential to differentiate into cartilage under stimulation with some reported growth and transcriptional factors, which may constitute an alternative for cartilage replacement approaches. In this study, we analyzed the in vitro chondrogenesis of ASCs transduced with adenoviral vectors encoding insulin-like growth factor-1 (IGF-1), transforming growth factor beta-1 (TGF-β1), fibroblast growth factor-2 (FGF-2), and sex-determining region Y-box 9 (SOX9) either alone or in combinations. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
France | 1 | 33% |
United Kingdom | 1 | 33% |
Mexico | 1 | 33% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Scientists | 1 | 33% |
Science communicators (journalists, bloggers, editors) | 1 | 33% |
Members of the public | 1 | 33% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Italy | 2 | 5% |
Portugal | 1 | 3% |
Mexico | 1 | 3% |
Unknown | 33 | 89% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 8 | 22% |
Student > Ph. D. Student | 6 | 16% |
Student > Master | 5 | 14% |
Student > Bachelor | 3 | 8% |
Student > Postgraduate | 3 | 8% |
Other | 4 | 11% |
Unknown | 8 | 22% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 10 | 27% |
Biochemistry, Genetics and Molecular Biology | 9 | 24% |
Medicine and Dentistry | 7 | 19% |
Engineering | 3 | 8% |
Materials Science | 1 | 3% |
Other | 1 | 3% |
Unknown | 6 | 16% |