Title |
Experimental characterization of the human non-sequence-specific nucleic acid interactome
|
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Published in |
Genome Biology, July 2013
|
DOI | 10.1186/gb-2013-14-7-r81 |
Pubmed ID | |
Authors |
Gerhard Dürnberger, Tilmann Bürckstümmer, Kilian Huber, Roberto Giambruno, Tobias Doerks, Evren Karayel, Thomas R Burkard, Ines Kaupe, André C Müller, Andreas Schönegger, Gerhard F Ecker, Hans Lohninger, Peer Bork, Keiryn L Bennett, Giulio Superti-Furga, Jacques Colinge |
Abstract |
The interactions between proteins and nucleic acids have a fundamental function in many biological processes, including gene transcription, RNA homeostasis, protein translation and pathogen sensing for innate immunity. While our knowledge of the ensemble of proteins that bind individual mRNAs in mammalian cells has been greatly augmented by recent surveys, no systematic study on the non-sequence-specific engagement of native human proteins with various types of nucleic acids has been reported. |
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United Kingdom | 3 | 27% |
Spain | 1 | 9% |
Germany | 1 | 9% |
Indonesia | 1 | 9% |
France | 1 | 9% |
Unknown | 4 | 36% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 5 | 45% |
Scientists | 4 | 36% |
Science communicators (journalists, bloggers, editors) | 1 | 9% |
Practitioners (doctors, other healthcare professionals) | 1 | 9% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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United States | 3 | 4% |
Denmark | 1 | 1% |
Unknown | 73 | 95% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 18 | 23% |
Student > Ph. D. Student | 14 | 18% |
Student > Master | 8 | 10% |
Other | 6 | 8% |
Student > Bachelor | 4 | 5% |
Other | 17 | 22% |
Unknown | 10 | 13% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 30 | 39% |
Biochemistry, Genetics and Molecular Biology | 19 | 25% |
Computer Science | 8 | 10% |
Engineering | 4 | 5% |
Immunology and Microbiology | 3 | 4% |
Other | 2 | 3% |
Unknown | 11 | 14% |