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Evaluation of estrogenic, antiestrogenic and genotoxic activity of nemorosone, the major compound found in brown Cuban propolis

Overview of attention for article published in BMC Complementary Medicine and Therapies, July 2013
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2 X users
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1 Facebook page

Citations

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18 Dimensions

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56 Mendeley
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Title
Evaluation of estrogenic, antiestrogenic and genotoxic activity of nemorosone, the major compound found in brown Cuban propolis
Published in
BMC Complementary Medicine and Therapies, July 2013
DOI 10.1186/1472-6882-13-201
Pubmed ID
Authors

Mariana S Camargo, Aline M Prieto, Flavia A Resende, Paula K Boldrin, Cassia RP Cardoso, Mariana F Fernández, José Manuel Molina-Molina, Nicolás Olea, Wagner Vilegas, Osmany Cuesta-Rubio, Eliana A Varanda

Abstract

Brown propolis is the major type of propolis found in Cuba; its principal component is nemorosone, the major constituent of Clusia rosea floral resins. Nemorosone has received increasing attention due to its strong in vitro anti-cancer action. The citotoxicity of nemorosone in several human cancer cell lines has been reported and correlated to the direct action it has on the estrogen receptor (ER). Breast cancer can be treated with agents that target estrogen-mediated signaling, such as antiestrogens. Phytoestrogen can mimic or modulate the actions of endogenous estrogens and the treatment of breast cancer with phytoestrogens may be a valid strategy, since they have shown anti-cancer activity.

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 56 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 56 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 9 16%
Student > Ph. D. Student 8 14%
Student > Bachelor 6 11%
Researcher 6 11%
Professor 4 7%
Other 11 20%
Unknown 12 21%
Readers by discipline Count As %
Chemistry 10 18%
Medicine and Dentistry 7 13%
Agricultural and Biological Sciences 6 11%
Biochemistry, Genetics and Molecular Biology 5 9%
Pharmacology, Toxicology and Pharmaceutical Science 3 5%
Other 6 11%
Unknown 19 34%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 05 August 2013.
All research outputs
#14,756,074
of 22,715,151 outputs
Outputs from BMC Complementary Medicine and Therapies
#1,831
of 3,620 outputs
Outputs of similar age
#117,710
of 197,887 outputs
Outputs of similar age from BMC Complementary Medicine and Therapies
#41
of 83 outputs
Altmetric has tracked 22,715,151 research outputs across all sources so far. This one is in the 32nd percentile – i.e., 32% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,620 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.5. This one is in the 43rd percentile – i.e., 43% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 197,887 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 38th percentile – i.e., 38% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 83 others from the same source and published within six weeks on either side of this one. This one is in the 44th percentile – i.e., 44% of its contemporaries scored the same or lower than it.