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An avoidable cause of thymoglobulin anaphylaxis

Overview of attention for article published in Allergy, Asthma & Clinical Immunology, February 2017
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Title
An avoidable cause of thymoglobulin anaphylaxis
Published in
Allergy, Asthma & Clinical Immunology, February 2017
DOI 10.1186/s13223-017-0186-9
Pubmed ID
Authors

S. Brabant, A. Facon, F. Provôt, M. Labalette, B. Wallaert, C. Chenivesse

Abstract

Thymoglobulin® (anti-thymocyte globulin [rabbit]) is a purified pasteurised, gamma immune globulin obtained by immunisation of rabbits with human thymocytes. Anaphylactic allergic reactions to a first injection of thymoglobulin are rare. We report a case of serious anaphylactic reaction occurring after a first intraoperative injection of thymoglobulin during renal transplantation in a patient with undiagnosed respiratory allergy to rabbit allergens. This case report reinforces the importance of identifying rabbit allergy by a simple combination of clinical interview followed by confirmatory skin testing or blood tests of all patients prior to injection of thymoglobulin, which is formally contraindicated in patients with a history of hypersensitivity to rabbit proteins.

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The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 12 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 12 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 3 25%
Other 1 8%
Student > Bachelor 1 8%
Student > Doctoral Student 1 8%
Student > Master 1 8%
Other 1 8%
Unknown 4 33%
Readers by discipline Count As %
Medicine and Dentistry 5 42%
Immunology and Microbiology 2 17%
Pharmacology, Toxicology and Pharmaceutical Science 1 8%
Unknown 4 33%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 24 February 2017.
All research outputs
#20,660,571
of 25,382,440 outputs
Outputs from Allergy, Asthma & Clinical Immunology
#784
of 924 outputs
Outputs of similar age
#251,914
of 324,444 outputs
Outputs of similar age from Allergy, Asthma & Clinical Immunology
#13
of 17 outputs
Altmetric has tracked 25,382,440 research outputs across all sources so far. This one is in the 10th percentile – i.e., 10% of other outputs scored the same or lower than it.
So far Altmetric has tracked 924 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 13.8. This one is in the 4th percentile – i.e., 4% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 324,444 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 12th percentile – i.e., 12% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 17 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.