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Low-frequency intermediate penetrance variants in the ROCK1 gene predispose to Tetralogy of Fallot

Overview of attention for article published in BMC Genomic Data, June 2013
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Title
Low-frequency intermediate penetrance variants in the ROCK1 gene predispose to Tetralogy of Fallot
Published in
BMC Genomic Data, June 2013
DOI 10.1186/1471-2156-14-57
Pubmed ID
Authors

Julian Palomino Doza, Ana Topf, Jamie Bentham, Shoumo Bhattacharya, Catherine Cosgrove, J David Brook, Javier Granados-Riveron, Frances A Bu’Lock, John O’Sullivan, A Graham Stuart, Jonathan Parsons, Caroline Relton, Judith Goodship, Deborah J Henderson, Bernard Keavney

Abstract

Epidemiological studies indicate a substantial excess familial recurrence of non-syndromic Tetralogy of Fallot (TOF), implicating genetic factors that remain largely unknown. The Rho induced kinase 1 gene (ROCK1) is a key component of the planar cell polarity signalling pathway, which plays an important role in normal cardiac development. The aim of this study was to investigate the role of genetic variation in ROCK1 on the risk of TOF.

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X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 31 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 3%
Unknown 30 97%

Demographic breakdown

Readers by professional status Count As %
Researcher 8 26%
Student > Bachelor 4 13%
Other 3 10%
Student > Ph. D. Student 3 10%
Professor 2 6%
Other 6 19%
Unknown 5 16%
Readers by discipline Count As %
Medicine and Dentistry 11 35%
Biochemistry, Genetics and Molecular Biology 6 19%
Agricultural and Biological Sciences 4 13%
Psychology 2 6%
Unspecified 1 3%
Other 2 6%
Unknown 5 16%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 05 August 2013.
All research outputs
#17,285,668
of 25,373,627 outputs
Outputs from BMC Genomic Data
#668
of 1,204 outputs
Outputs of similar age
#132,817
of 209,379 outputs
Outputs of similar age from BMC Genomic Data
#13
of 20 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. This one is in the 21st percentile – i.e., 21% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,204 research outputs from this source. They receive a mean Attention Score of 4.3. This one is in the 34th percentile – i.e., 34% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 209,379 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 27th percentile – i.e., 27% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 20 others from the same source and published within six weeks on either side of this one. This one is in the 30th percentile – i.e., 30% of its contemporaries scored the same or lower than it.